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1.37013

SAFC

Sodium hydrogen carbonate

EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

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Synonym(s):
Sodium bicarbonate
Linear Formula:
NaHCO3
CAS Number:
144-55-8
Molecular Weight:
84.01
Beilstein:
4153970
MDL number:
MFCD00003528
EC Index Number:
205-633-8

Agency

BP
ChP
JP
Ph. Eur.
USP

Quality Level

500

description

EMPROVE® EXPERT Ph Eur,BP,USP,JP

product line

EMPROVE® EXPERT

potency

4220 mg/kg LD50, oral (Rat)

pH

8.6 (20 °C, 50 g/L in H2O)

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

mp

270 °C (decomposition)

density

2.22 g/cm3 at 20 °C
2.16 g/mL at 25 °C (lit.)

bulk density

1000 kg/m3

application(s)

parenterals

storage temp.

2-30°C

SMILES string

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

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General description

Our SAFC® portfolio of high-quality products for biopharmaceutical processing withstands strict quality control procedures and is produced according to MQ-500 requirements as defined by the M-Clarity program.

M-Clarity Program

As part of our EMPROVE® Program, our raw materials are offered with EMPROVE® Dossiers which provide comprehensive, up-to-date documentation to help you navigate regulatory challenges, manage risks, and improve your manufacturing processes.

Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step.

Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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