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SAFC

Polyvinyl alcohol

26-88, EMPROVE® ESSENTIAL, Ph. Eur., ChP, USP, JPE

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Synonym(s):
Poly(vinyl alcohol), PVA, PVOH
Linear Formula:
[-CH2CHOH-]n
CAS Number:
9002-89-5
MDL number:
MFCD00081922

Agency

ChP
JPE
Ph. Eur.
USP

Quality Level

500

description

EMPROVE® ESSENTIAL Ph Eur,USP,JPE

product line

EMPROVE® ESSENTIAL

form

scales

technique(s)

API processing | nano-milling: suitable

mp

160-240 °C

application(s)

controlled release
liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solid formulation

storage temp.

15-25°C

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

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General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyvinyl alcohol 26-88 is a synthetic, bio-compatible, toxicologically safe, and multi-compendial polymer. It is part of a portfolio spanning a wide range of pharmaceutical grade polyvinyl alcohols of different viscosities, hydrolysis grades and molecular weights and is well suited for a broad variety of pharmaceutical applications, including solid, liquid, and semi-solid formulations.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

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Articles

Use of PVA to Overcome Challenges in Ophthalmic Formulations

PVA meets all the essential requirements to be used in ophthalmic preparations and offers important benefits compared to HPMC and CMC.

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