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Merck
CN

16-293

Anti-Akt/PKB Antibody, PH Domain, clone SKB1, Alexa Fluor™ 488

clone SKB1, Upstate®, from mouse

Synonym(s):

PKB, PKD-alpha, AKT1, Protein Kinase B

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

Key Documents

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Product Name

Anti-Akt/PKB Antibody, PH Domain, clone SKB1, Alexa Fluor™ 488, clone SKB1, Upstate®, from mouse

biological source

mouse

conjugate

ALEXA FLUOR™ 488

antibody form

purified antibody

antibody product type

primary antibodies

clone

SKB1, monoclonal

species reactivity

mouse, rat, human

manufacturer/tradename

Upstate®

technique(s)

flow cytometry: suitable
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

NM_001014431.1
NM_001014432.1
NM_005163.2

UniProt accession no.

P31749

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

mouse ... Akt1(11651)

Related Categories

Biochem/physiol Actions

Recognizes Akt1/PKBα > Akt2/PKBβ (30%) > Akt3/PKBγ (weak to none) based on immunoblot analysis using 100ng recombinant fusion protein for each isoform.

General description

60 kDa

Immunogen

GST-fusion protein corresponding to residues 1-149 of human Akt1. Clone SKB1.

Legal Information

ALEXA FLUOR is a trademark of Life Technologies
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Application

Anti-Akt/PKB Antibody, PH Domain, clone SKB1, Alexa Fluor 488 is an antibody against Akt/PKB for use in FC, IC, IF & WB.

Analysis Note

Routinely evaluated by Immunocytochemistry and Flow Cytometry

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Storage Class

10 - Combustible liquids

Regulatory Information

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Certificates of Analysis (COA)

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Elke Butt et al.
Cells, 9(2) (2020-02-23)
The serine/threonine protein kinase AKT1 is a downstream target of the chemokine receptor 4 (CXCR4), and both proteins play a central role in the modulation of diverse cellular processes, including proliferation and cell survival. While in chronic myeloid leukemia (CML)
Chanya Inprasit et al.
International journal of molecular medicine, 45(3), 779-792 (2020-01-11)
Obesity is a global health problem affecting the general population. Acupoint catgut embedding (ACE) is an alternative treatment that involves the implantation of absorbable catgut suture at acupoints. The transient receptor vanilloid member 1 (TRPV1) is a calcium ion channel

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