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BIS-TRIS propane

ULTROL® Grade, >98% (titration), non-zwitterionic buffer useful in pH range 6.3-9.5

Synonym(s):

BIS-Tris Propane, ULTROL® Grade, 1,3- bis[ tris(Hydroxymethyl)methylamino]propane, 1,3-bis[tris(Hydroxymethyl)methylamino]propane

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About This Item

Empirical Formula (Hill Notation):
C11H26N2O6
CAS Number:
64431-96-5
Molecular Weight:
282.33
UNSPSC Code:
12161705
NACRES:
NA.25
MDL number:
MFCD00004689
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Quality Segment

100

assay

>98% (titration)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

white

pKa (20 °C)

6.8

solubility

water: 1 M

cation traces

heavy metals: <1 ppm

shipped in

ambient

storage temp.

15-25°C

SMILES string

N(C(CO)(CO)CO)CCCNC(CO)(CO)CO

InChI

1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2

InChI key

HHKZCCWKTZRCCL-UHFFFAOYSA-N

General description

A non-zwitterionic buffer (Absorbance: <0.08 at 260 nm, 1.0 M, H2O) that is useful near physiological pH (6.3-9.5). Has a pKa of 6.8 at 25°C.
A non-zwitterionic buffer that is useful in the pH 6.3-9.5 range. Has pKas of 6.8 (pKa1) and 9.0 (pKa2).
Absorbance (1.0 M, H2O, 260 nm): <0.08.

Application


  • Comparing solution-gate and bottom-gate nanowire field-effect transistors on pH sensing with different salt concentrations and surface modifications.: BIS-TRIS propane is used as a buffering agent in the development of nanowire field-effect transistors for pH sensing. The research demonstrates its effectiveness in enhancing the sensitivity and stability of these biosensors under varying conditions (Hu et al., 2024).

  • Laser-induced tuning of graphene field-effect transistors for pH sensing.: This study employs BIS-TRIS propane as a buffering solution to optimize the performance of graphene field-effect transistors in pH sensing applications. The findings highlight the role of BIS-TRIS propane in achieving precise tuning of sensor responses (Lampinen et al., 2023).

  • Elucidating the exchange interactions in a {Gd(III)Cu(II)(4)} propellor.: BIS-TRIS propane is utilized as a buffer in the investigation of exchange interactions in complex metal assemblies. The study provides insights into the magnetic properties and potential applications in materials science (Heras Ojea et al., 2023).

  • Protein association on multimodal chromatography media.: This research explores the use of BIS-TRIS propane in multimodal chromatography to study protein interactions. The buffer′s compatibility with various chromatographic techniques enhances the understanding of protein behavior and purification processes (Muca & Antos, 2023).


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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