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5.08160

Sigma-Aldrich

DPDPE

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Synonym(s):
DPDPE, δ Opioid Receptor Agonist, DPDPE
Empirical Formula (Hill Notation):
C30H39N5O7S2
CAS Number:
Molecular Weight:
645.79

Assay

≥99% (HPLC)

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

off-white

solubility

water: 1 mg/mL

storage temp.

−20°C

InChI

1S/C30H39N5O7S2/c1-29(2)23(34-25(38)20(31)14-18-10-12-19(36)13-11-18)27(40)32-16-22(37)33-21(15-17-8-6-5-7-9-17)26(39)35-24(28(41)42)30(3,4)44-43-29/h5-13,20-21,23-24,36H,14-16,31H2,1-4H3,(H,32,40)(H,33,37)(H,34,38)(H,35,39)(H,41,42)/t20-,21-,23-,24-/m0/s1

InChI key

MCMMCRYPQBNCPH-WMIMKTLMSA-N

General description

A potent agonist selective for δ opioid receptor (EC50 = 5.2 nM). Exhibits anti-convulsant effects in vivo in rats, also used in nociceptive studies.

Biochem/physiol Actions

Primary Target
δ opioid receptor

Warning

Toxicity: Standard Handling (A)

Sequence

Tyr-D-Pen-Gly-Phe-D-Pen (2-5 disulfide bond)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Chen, C., 1997. J. Pharmacol. Exp. Ther.283, 1151.
Chandrakumar, S., et al., 1992. J. Med. Chem.35, 2928.
Tortella, F. 1988. Peptides.9, 1177.
Clark, A., et al., 1986. Eur. J. Pharmacol.128, 303.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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