Skip to Content
Merck
CN

Key Documents

View All Documentation

8.08261

Trifluoroacetic anhydride

for synthesis

Synonym(s):

Trifluoroacetic anhydride, Bis(trifluoroacetic) anhydride, TFAA

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Linear Formula:
(CF3CO)2O
CAS Number:
407-25-0
Molecular Weight:
210.03
UNSPSC Code:
12352106
EC Index Number:
206-982-9
NACRES:
NA.22
MDL number:
MFCD00000416
Assay:
≥99.0% (GC)
Grade:
synthesis grade
Bp:
40 °C/1013 hPa
Vapor pressure:
405 hPa ( 20 °C)
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

synthesis grade

Quality Level

200

vapor pressure

405 hPa ( 20 °C)

assay

≥99.0% (GC)

form

liquid

dilution

(for synthesis)

bp

40 °C/1013 hPa

mp

-65 °C

density

1.51 g/cm3 at 20 °C

storage temp.

2-30°C

SMILES string

FC(F)(F)C(=O)OC(=O)C(F)(F)F

InChI

1S/C4F6O3/c5-3(6,7)1(11)13-2(12)4(8,9)10

InChI key

QAEDZJGFFMLHHQ-UHFFFAOYSA-N

Application


  • Cascade Rearrangement: Nitro Group-Participating Syntheses of 1,2,5-Thiadiazoles and 1,2,4-Thiadiazolones.: This study explores the role of trifluoroacetic anhydride in the synthesis of thiadiazoles and thiadiazolones via a nitro group-participating cascade rearrangement, highlighting its utility in organic synthesis (Li et al., 2024).

  • Copper Loading-Controlled Selective Synthesis of 2,5-Bis(trifluoromethyl) and Monotrifluoromethyl-Substituted Oxazoles.: This research demonstrates the selective synthesis of trifluoromethyl-substituted oxazoles using trifluoroacetic anhydride, showcasing its versatility in controlling copper loading during reactions (Wu et al., 2024).

  • Wood Esterification by Fatty Acids Using Trifluoroacetic Anhydride as an Impelling Agent and Its Application for the Synthesis of a New Bioplastic.: The study presents a novel method for wood esterification using trifluoroacetic anhydride, facilitating the development of new bioplastic materials (Sejati et al., 2023).

  • Synthesis of alpha-Seleno Boronates via Diboration of Carbonyl Compounds.: This paper details the synthesis of alpha-seleno boronates using trifluoroacetic anhydride in the diboration of carbonyl compounds, emphasizing its reactivity and selectivity in chemical transformations (Paul et al., 2023).

  • Regioselective Synthesis of 3-Nitroindoles Under Non-Acidic and Non-Metallic Conditions.: The research highlights the use of trifluoroacetic anhydride in the regioselective synthesis of 3-nitroindoles, demonstrating its efficiency under non-acidic and non-metallic conditions (Zhang et al., 2023).

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.509 - 1.512
Identity (IR): passes test

Still not finding the right product?

Explore all of our products under Trifluoroacetic anhydride

pictograms

CorrosionExclamation mark
GHS05,GHS07

signalword

Danger

Hazard Classifications

Acute Tox. 4 Inhalation - Aquatic Chronic 3 - Eye Dam. 1 - Skin Corr. 1A

supp_hazards

EUH014

wgk

WGK 2

Storage Class

8B - Non-combustible corrosive hazardous materials

Regulatory Information

危险化学品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKUGTIN
808261002604054839449635
808261050104054839449659
808261010104054839449642