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Merck
CN

8.43942

Propanephosphonic acid anhydride

(50% solution in ethyl acetate) for synthesis T3P

Synonym(s):

2,4,6-Tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide solution, PPACA, Propylphosphonic anhydride, T3P

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About This Item

NACRES:
NA.22
UNSPSC Code:
12352108
Form:
liquid
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vapor pressure

97 hPa ( 20 °C)

Quality Level

form

liquid

bp

77 °C/1013 hPa (ethyl acetate)

transition temp

flash point -4 °C (ethyl acetate)

density

1.08 g/cm3 at 20 °C

storage temp.

2-8°C

Application

  • Cyclization of Linear Tetrapeptides Containing N‐Methylated Amino Acids: The study reports the synthesis of naturally occurring cyclotetrapeptides using 1-propanephosphonic acid anhydride, noting unexpected findings in cyclization patterns. (Zhang et al., 2017).

Analysis Note

Assay (T3P) (NMR): ≥ 40.0 %
Pyropropanephosphonic acid (NMR): ≤ 10.0 %
Propanephosphonic acid (NMR): ≤ 0.50 %
Ethyl acetate (calculated): ≤ 50.0 %


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signalword

Danger

Hazard Classifications

Eye Dam. 1 - Flam. Liq. 2 - Met. Corr. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

24.8 °F - closed cup - ethyl acetate

flash_point_c

-4 °C - closed cup - ethyl acetate

Regulatory Information

新产品

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Global Trade Item Number

SKUGTIN
843942005004027269234706
843942010004027269228477
843942002504027269228460