Skip to Content
Merck
CN

Key Documents

View All Documentation

8.51014

Fmoc-OSu

≥99.0% (HPLC), for peptide synthesis, Novabiochem®

Synonym(s):

Fmoc-OSu, FMOC-ONSu, N-(9H-Fluoren-9-ylmethoxycarbonyloxy)succinimide, N-(9-Fluorenylmethoxycarbonyloxy)succinimide, 9-Fluorenylmethyl-succinimidyl carbonate

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C19H15NO5
CAS Number:
82911-69-1
Molecular Weight:
337.33
UNSPSC Code:
12352108
EC Index Number:
433-520-5
NACRES:
NA.22
MDL number:
MFCD00010733
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

Fmoc-OSu, Novabiochem®

Quality Level

200

product line

Novabiochem®

assay

≥99.0% (HPLC)

form

powder

manufacturer/tradename

Novabiochem®

mp

145-148 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

SMILES string

N4(C(=O)CCC4=O)OC(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C19H15NO5/c21-17-9-10-18(22)20(17)25-19(23)24-11-16-14-7-3-1-5-12(14)13-6-2-4-8-15(13)16/h1-8,16H,9-11H2

InChI key

WMSUFWLPZLCIHP-UHFFFAOYSA-N

General description

Reagent for the preparation of pure Fmoc-amino acids that are free from contamination by Fmoc-dipeptides [1,2,3].

Literature references

[1] A. Paquet (1982) Can. J. Chem., 60, 976.
[2] L. Lapatsanis, et al. (1983) Synthesis, 671.
[3] G. F. Sigler, et al. (1983) Biopolymers, 22, 2157.

Application

  • Sequence-defined positioning of amine and amide residues to control catechol driven wet adhesion: This study uses Fmoc-OSu for selective functionalization of amines, demonstrating its role in synthesizing complex molecules with specific adhesive properties (Fischer et al., 2020).
  • Fmoc-OASUD: A new reagent for the preparation of Fmoc-amino acids free from impurities resulting from Lossen rearrangement: Discusses the development of Fmoc-OASUD as a superior alternative to Fmoc-OSu, reducing impurities in peptide synthesis processes (Rao et al., 2016).

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 99.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

Other Notes

Replaces: 01-63-0001

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Exclamation markEnvironment
GHS07,GHS09

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

新产品

This item has

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Ahmet Kertmen et al.
Langmuir : the ACS journal of surfaces and colloids, 35(15), 5281-5293 (2019-03-27)
Numerous glutamine analogues have been reported as irreversible inhibitors of the glucosamine-6-phosphate (GlcN-6-P) synthase in pathogenic Candida albicans in the last 3.5 decades. Among the reported inhibitors, the most effective N3-(4-methoxyfumaroyl)-l-2,3-diaminopropanoic acid (FMDP) has been extensively studied in order to

Global Trade Item Number

SKUGTIN
851014010004027269081331
851014002504027269081324