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Merck
CN

8.52013

Fmoc-Lys(Z)-OH

Novabiochem®

Synonym(s):

Fmoc-Lys(Z)-OH, N-α-Fmoc-N-ε-benzyloxycarbonyl-L-lysine

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About This Item

Empirical Formula (Hill Notation):
C29H30N2O6
CAS Number:
Molecular Weight:
502.56
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
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Quality Segment

product line

Novabiochem®

assay

≥95.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

105-115 °C

application(s)

peptide synthesis

functional group

amine

storage temp.

2-30°C

SMILES string

N([C@@H](CCCCNC(=O)OCc4ccccc4)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C29H30N2O6/c32-27(33)26(16-8-9-17-30-28(34)36-18-20-10-2-1-3-11-20)31-29(35)37-19-25-23-14-6-4-12-21(23)22-13-5-7-15-24(22)25/h1-7,10-15,25-26H,8-9,16-19H2,(H,30,34)(H,31,35)(H,32,33)/t26-/m0/s1

InChI key

KRULQRVJXQQPQH-SANMLTNESA-N

General description

Building block for introduction of lysine amino-acid residues by Fmoc SPPS. The side-chain protecting group is TFA-stable but can be removed by hydrogenation over Pd/C or with strong acids such as TFMSA.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1027

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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