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Merck
CN

8.52129

Fmoc-Lys(Boc)-OPfp

Novabiochem®

Synonym(s):

Fmoc-Lys(Boc)-OPfp, N-α-Fmoc-N-ε-t.-Boc-L-lysine pentafluorophenyl ester

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About This Item

Empirical Formula (Hill Notation):
C32H31F5N2O6
CAS Number:
Molecular Weight:
634.59
MDL number:
UNSPSC Code:
12352209
NACRES:
NA.22
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Quality Segment

product line

Novabiochem®

assay

≥97.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

135-145 °C

application(s)

peptide synthesis

functional group

amine

storage temp.

15-25°C

SMILES string

Fc1c(c(c(c(c1F)F)OC(=O)[C@@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)CCCCNC(=O)OC(C)(C)C)F)F

InChI

1S/C32H31F5N2O6/c1-32(2,3)45-30(41)38-15-9-8-14-22(29(40)44-28-26(36)24(34)23(33)25(35)27(28)37)39-31(42)43-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,38,41)(H,39,42)/t22-/m0/s1

InChI key

HLNVSYQQDWNJRI-QFIPXVFZSA-N

General description

Pre-formed pentafluorophenyl ester for coupling of lysine amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -16.0 - -13.0 °
Purity (TLC (0004)): <2% DCU
Assay (HPLC, area%): ≥ 97.0% (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1511

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


Hazard Classifications

Skin Irrit. 2

pictograms

Exclamation mark

signalword

Warning

hcodes

Storage Class

11 - Combustible Solids

wgk

WGK 3



Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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