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Merck
CN

8.52139

Fmoc-N-Me-Leu-OH

Novabiochem®

Synonym(s):

Fmoc-N-Me-Leu-OH, N-α-Fmoc-N-α-methyl-L-leucine

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About This Item

Empirical Formula (Hill Notation):
C22H25NO4
CAS Number:
Molecular Weight:
367.44
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
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Quality Segment

product line

Novabiochem®

assay

≥95.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

113-116 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-30°C

SMILES string

N([C@@H](CC(C)C)C(=O)O)(C)C(=O)OCC1c2c(cccc2)c3c1cccc3

InChI

1S/C22H25NO4/c1-14(2)12-20(21(24)25)23(3)22(26)27-13-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,14,19-20H,12-13H2,1-3H3,(H,24,25)/t20-/m0/s1

InChI key

BUJQSIPFDWLNDC-FQEVSTJZSA-N

General description

Building block for introduction of N-α-methyl-leucine amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(157A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-9031

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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