8.52208
Fmoc-3,4-dehydro-Pro-OH
Novabiochem®
Synonym(s):
Fmoc-3,4-dehydro-Pro-OH, N-α-Fmoc-3,4-dehydro-L-proline
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About This Item
Quality Level
product line
Novabiochem®
assay
≥85.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)
form
powder
reaction suitability
reaction type: Fmoc solid-phase peptide synthesis
manufacturer/tradename
Novabiochem®
application(s)
peptide synthesis
functional group
Fmoc
storage temp.
15-25°C
SMILES string
N4([C@@H](C=CC4)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
InChI
1S/C20H17NO4/c22-19(23)18-10-5-11-21(18)20(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-10,17-18H,11-12H2,(H,22,23)/t18-/m0/s1
InChI key
OALUMAMYGOBVTF-SFHVURJKSA-N
General description
Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Analysis Note
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 97.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 85.0 %
Water (K. F.): ≤ 5.0 %
To see the solvent systems used for TLC of Novabiochem® products please click here.
Other Notes
Legal Information
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
This item has
Certificates of Analysis (COA)
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Articles
Proline analogues are promising candidates for tuning the biological, pharmaceutical, or physicochemical properties of naturally occuring, as well as de novo designed, linear, and, cyclic peptides.
Unnatural amino acids, the non-proteinogenic amino acids that either occur naturally or are chemically synthesized, are becoming more and more important as tools for modern drug discovery research.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 8522080001 | 04027269093785 |