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Merck
CN

8.52228

Fmoc-Val-OPfp

Novabiochem®

Synonym(s):

Fmoc-Val-OPfp, N-α-Fmoc-L-valine pentafluorophenyl ester

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About This Item

Empirical Formula (Hill Notation):
C26H20F5NO4
CAS Number:
Molecular Weight:
505.43
UNSPSC Code:
12352209
NACRES:
NA.22
MDL number:
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Quality Segment

product line

Novabiochem®

assay

≥98.0% (HPLC)

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

mp

110-120 °C

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

15-25°C

SMILES string

Fc1c(c(c(c(c1F)F)OC(=O)[C@@H](NC(=O)OCC2c3c(cccc3)c4c2cccc4)C(C)C)F)F

InChI

1S/C26H20F5NO4/c1-12(2)23(25(33)36-24-21(30)19(28)18(27)20(29)22(24)31)32-26(34)35-11-17-15-9-5-3-7-13(15)14-8-4-6-10-16(14)17/h3-10,12,17,23H,11H2,1-2H3,(H,32,34)/t23-/m0/s1

InChI key

TZEGAVSWQUEHAQ-QHCPKHFHSA-N

General description

Pre-formed pentafluorophenyl ester for coupling of valine amino-acid residues by Fmoc SPPS. Use enables bromophenol blue monitoring of amide bond formation.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in chloroform): -25.5 - -20.5 °
DCU (DC (0004)): ≤ 2 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (0,5 mmole in 3 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

Other Notes

Replaces: 04-12-1520

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3



Certificates of Analysis (COA)

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