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Merck
CN

8.52372

Fmoc-selenomethionine

Novabiochem®

Synonym(s):

Fmoc-selenomethionine, N-Fmoc-L-amino-4-(methylselanyl)butanoic acid

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About This Item

Empirical Formula (Hill Notation):
C20H21NO4Se
CAS Number:
Molecular Weight:
418.35
UNSPSC Code:
12352209
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Quality Segment

product line

Novabiochem®

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

2-8°C

InChI

1S/C20H21NO4Se/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m0/s1

InChI key

MOIJGLAOGAWHTN-SFHVURJKSA-N

General description

Fmoc-selenomethionine can be introduced under standard conditions. Any selenoxide formed during synthesis can be easily reduced back to selenide by treatment with β-mercaptoethanol. Introduction of selenium can help facilitate solid phase and solution structural determination and the study of peptide-protein interactions [1].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Literature references

[1] L. Moroder (2005) J. Pept.Sci., 11, 187.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_c

Not applicable



Certificates of Analysis (COA)

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