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Merck
CN

8.52403

Fmoc-D-His(Clt)-OH

Novabiochem®

Synonym(s):

Fmoc-D-His(Clt)-OH, N-α-Fmoc-N-im-2-chlorotrityl-D-histidine

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About This Item

Empirical Formula (Hill Notation):
C40H32ClN3O4
CAS Number:
Molecular Weight:
654.15
UNSPSC Code:
12352209
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Quality Segment

product line

Novabiochem®

form

powder

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

Fmoc

storage temp.

15-25°C

General description

Building block for introduction of D-histidine by Fmoc SPPS. The Clt group is more stable to acid than Trt and its use avoids the formation of partially protected histidine peptides during the preparation of protected fragments.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Colour (visual): white to off white
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 5.00 %

To see the solvent systems used for TLC of Novabiochem® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



Certificates of Analysis (COA)

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