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8.53023

Boc-Tyr(tBu)-OH

Name: Boc-Tyr(tBu)-OH
Brand: MM

≥98% (TLC), for peptide synthesis, Novabiochem^®

Synonym(s):

Boc-Tyr(tBu)-OH, N-α-t.-Boc-O-t.-butyl-L-tyrosine

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About This Item

Empirical Formula (Hill Notation):

C₁₈H₂₇NO₅

CAS Number:

47375-34-8

Molecular Weight:

337.41

UNSPSC Code:

12352209

NACRES:

NA.22

MDL number:

MFCD00065598

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Properties

Product Name

Boc-Tyr(tBu)-OH, Novabiochem^®

Quality Segment

200

product line

Novabiochem^®

assay

≥98% (TLC)

form

powder

reaction suitability

reaction type: Boc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem^®

mp

113-116 °C

application(s)

peptide synthesis

functional group

hydroxyl

storage temp.

2-30°C

SMILES string

N([C@@H](Cc1ccc(cc1)OC(C)(C)C)C(=O)O)C(=O)OC(C)(C)C

InChI

1S/C18H27NO5/c1-17(2,3)23-13-9-7-12(8-10-13)11-14(15(20)21)19-16(22)24-18(4,5)6/h7-10,14H,11H2,1-6H3,(H,19,22)(H,20,21)/t14-/m0/s1

InChI key

ZEQLLMOXFVKKCN-AWEZNQCLSA-N

Description

General description

Useful building block for introduction of N-terminal tyrosine residues in Fmoc SPPS.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): -15.5 - -12.5 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-0093

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c