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Dansyl NovaTag® resin

Novabiochem®

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Synonym(s):
N-Dansyl-NÆ-Fmoc-ethylenediamine MPB-AM resin

Quality Level

200

product line

NovaSyn® TG
Novabiochem®

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

functional group

amine

storage temp.

15-25°C

Related Categories

General description

Dansyl NovaTag resin is an ideal tool for the synthesis of Dansyl-labeled peptides. The resin pre-loaded with the Dansyl chromophore can be used directly in Fmoc SPPS. Following peptide assembly under standard Fmoc SPPS conditions, cleavage with TFA affords the Dansyl-labeled peptide. This resin has been recently used to dansyl-labeled amyloid-RGD peptides [1] and FRET probes for mercury binding protein MerP [2].

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

Literature references

[1] S. L. Gras, et al. (2008) Biomaterials, 29, 1553.
[2] B. R. White, et al. (2008) Analyst,, 133, 65

Linkage

Replaces: 04-12-3900

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.30 - 0.60 mmol/g
Swelling Volume (in DMF): lot specific result
The polymer matrix is copoly styrene - 1 & DVB 100 - 200 mesh

Legal Information

NOVASYN is a registered trademark of Merck KGaA, Darmstadt, Germany
NOVATAG is a registered trademark of Merck KGaA, Darmstadt, Germany
Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Articles

Peptide Labeling

Chromogenic and fluorogenic derivatives are invaluable tools for biochemistry, having numerous applications in enzymology, protein chemistry, immunology and histochemistry.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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