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Merck
CN

FCMAB182F

Milli-Mark® Anti-CD15-FITC Antibody, clone C3D-1

clone C3D-1, Milli-Mark®, from mouse

Synonym(s):

Alpha-(1,3)-fucosyltransferase, Galactoside 3-L-fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, FucT-IV, Fuc-TIV, ELAM-1 ligand fucosyltransferase

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.44

Key Documents

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biological source

mouse

Quality Level

100

conjugate

FITC conjugate

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

C3D-1, monoclonal

species reactivity

human

manufacturer/tradename

Milli-Mark®

technique(s)

flow cytometry: suitable

isotype

IgMκ

NCBI accession no.

NP_002024.1

UniProt accession no.

P22083

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... FUT4(2526)

Related Categories

General description

CD15 is a carbohydrate antigen carried by both glycoproteins and glycoliplds. The structure of the antigen was determined to be Galb1→4[Fuca1→3]GIcNACb1→3Galb1→R. CD15 serves as a ligand for selectins and might also be involved in cell adhesion through a direct Lewis X-Lewis X interaction. CD15 is expressed mainly on mature granulocytes and monocytes but also on immature bone marrow cells (Kannagi, 1997).
Anti-CD15, C3D-1, was included in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD15 (Kannagi, 1997).

Immunogen

Purified human neutrophils

Application

This Milli-Mark Anti-CD15-FITC Antibody, clone C3D-1 is validated for use in FC for the detection of CD15.

Biochem/physiol Actions

Antibody recognizes Human CD15 antigen.

Physical form

Activated Sepharose
Purified Mouse monoclonal IgM conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Analysis Note

Evaluated by flow cytometry using human PBMCs

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Rebeca Piatniczka Iglesia et al.
Stem cell research & therapy, 8(1), 76-76 (2017-04-18)
Glioblastoma (GBM), a highly aggressive brain tumor, contains a subpopulation of glioblastoma stem-like cells (GSCs) that play roles in tumor maintenance, invasion, and therapeutic resistance. GSCs are therefore a promising target for GBM treatment. Our group identified the cellular prion
Marlieke L M Jongsma et al.
Immunity, 54(1), 132-150 (2020-12-04)
HLA class I (HLA-I) glycoproteins drive immune responses by presenting antigens to cognate CD8+ T cells. This process is often hijacked by tumors and pathogens for immune evasion. Because options for restoring HLA-I antigen presentation are limited, we aimed to identify

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