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Merck
CN

30-5140

Triton™ X-100

CP

Synonym(s):

t-Octylphenoxypolyethoxyethanol, Polyethylene glycol tert-octylphenyl ether

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About This Item

Linear Formula:
t-Oct-C6H4-(OCH2CH2)xOH, x= 9-10
CAS Number:
9036-19-5
PubChem Substance ID:
329753529
UNSPSC Code:
12161900
Beilstein/REAXYS Number:
2315025
MDL number:
MFCD00128254

Key Documents

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grade

CP

description

non-ionic surfactant

form

liquid

mol wt

micellar avg mol wt 80,000, average mol wt 625

availability

available only in Japan

aggregation number

100-155

CMC

0.2-0.9 mM (20-25°C)

transition temp

cloud point 65 °C, pour point ~7 °C

HLB

13.5

SMILES string

CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1

InChI

1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3

InChI key

HNLXNOZHXNSSPN-UHFFFAOYSA-N

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Biochem/physiol Actions

Widely used non-ionic surfactant for recovery of membrane components under mild non-denaturing conditions.

Legal Information

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

signalword

Danger

Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

539.6 °F

flash_point_c

282 °C

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - ED ENV 1 - Eye Dam. 1 - Skin Irrit. 2

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
A0557
A6552
A1529
A8446
A2425

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Jing Cui et al.
Experimental eye research, 88(3), 438-444 (2008-11-27)
Previous investigators reported that epiretinal membranes isolated from patients with proliferative vitreoretinopathy (PVR) express various platelet-derived growth factor (PDGF) family members and PDGF receptors (PDGFRs) (Cui, J.Z., Chiu, A., Maberley, D., Ma, P., Samad, A., Matsubara, J.A., 2007. Stage specificity
Friederike Pfeiffer et al.
Acta neuropathologica, 122(5), 601-614 (2011-10-11)
In experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS), loss of the blood-brain barrier (BBB) tight junction (TJ) protein claudin-3 correlates with immune cell infiltration into the CNS and BBB leakiness. Here we show that sealing BBB
Urszula Florczyk et al.
Free radical biology & medicine, 51(10), 1882-1892 (2011-09-20)
Recently we have shown that hypoxia as well as overexpression of the stable form of hypoxia-inducible factor-1α (HIF-1α) diminished the expression of interleukin-8 (IL-8) by inhibition of the Nrf2 transcription factor in HMEC-1 cells. Because HIF isoforms may exert different
Fabian Anderegg et al.
PloS one, 6(12), e28583-e28583 (2011-12-14)
The bone-degrading activity of osteoclasts depends on the formation of a cytoskeletal-adhesive super-structure known as the sealing zone (SZ). The SZ is a dynamic structure, consisting of a condensed array of podosomes, the elementary adhesion-mediating structures of osteoclasts, interconnected by
Lionel Rigottier-Gois et al.
PloS one, 6(12), e29023-e29023 (2011-12-24)
Spread of antibiotic resistance among bacteria responsible for nosocomial and community-acquired infections urges for novel therapeutic or prophylactic targets and for innovative pathogen-specific antibacterial compounds. Major challenges are posed by opportunistic pathogens belonging to the low GC% gram-positive bacteria. Among
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Global Trade Item Number

SKUGTIN
30-5140-5-500ML-J04061837604119

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