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Merck
CN

00900585

Berberine chloride

primary reference standard

Synonym(s):

Berberine chloride form, Natural Yellow 18

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About This Item

Empirical Formula (Hill Notation):
C20H18ClNO4
CAS Number:
Molecular Weight:
371.81
UNSPSC Code:
12352210
NACRES:
NA.24
MDL number:
Colour Index Number:
75160
Beilstein/REAXYS Number:
3836585
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Product Name

Berberine chloride, primary reference standard

InChI key

VKJGBAJNNALVAV-UHFFFAOYSA-M

SMILES string

COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]

InChI

1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1

grade

primary reference standard

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

HWI

Quality Level

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Application

Fluorescent stain for heparin in mast cells

Biochem/physiol Actions

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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