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Merck
CN

01310

N-Acetyl-L-methionine

≥98.5% (T)

Synonym(s):

N-acetyl-L-lysine

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About This Item

Linear Formula:
CH3SCH2CH2CH(NHCOCH3)CO2H
CAS Number:
65-82-7
Molecular Weight:
191.25
UNSPSC Code:
12352209
NACRES:
NA.22
PubChem Substance ID:
329747249
EC Number:
200-617-7
Beilstein/REAXYS Number:
1725552
MDL number:
MFCD00064441

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InChI key

XUYPXLNMDZIRQH-LURJTMIESA-N

InChI

1S/C7H13NO3S/c1-5(9)8-6(7(10)11)3-4-12-2/h6H,3-4H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1

SMILES string

CSCC[C@H](NC(C)=O)C(O)=O

assay

≥98.5% (T), ≥98.5% (TLC)

form

powder or crystals

optical activity

[α]20/D -21.0±1.0°, c = 1% in H2O

reaction suitability

reaction type: solution phase peptide synthesis

mp

103-106 °C (lit.)

solubility

methanol: 50 mg/mL, clear to very slightly hazy, colorless

application(s)

peptide synthesis

Quality Level

100

Related Categories

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN2406
BCCG7455
BCCJ4944
BCCF0218
BCCC4556

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Agnieszka Kołodziejczak-Radzimska et al.
Biotechnology progress, 34(3), 767-777 (2018-01-10)
Acylase I from Aspergillus melleus was immobilized on supports consisting of unmodified and modified silica. Modification was performed using 3-aminopropyltriethoxysilane (APTES) and glutaraldehyde (GA). The effectiveness of immobilization was investigated using the standard Bradford method in addition to a number
Mie R Rasmussen et al.
Journal of proteome research, 15(12), 4591-4600 (2016-11-05)
Loss-of-function mutations in the transmembrane ABCC6 transport protein cause pseudoxanthoma elasticum (PXE), an ectopic, metabolic mineralization disorder that affects the skin, eye, and vessels. ABCC6 is assumed to mediate efflux of one or several small molecule compounds from the liver
Rebecca D Sandlin et al.
Journal of inorganic biochemistry, 104(2), 214-216 (2009-11-13)
A bulky platinum triamine complex, [Pt(Me(5)dien)(NO(3))]NO(3) (Me(5)dien=N,N,N',N',N''-pentamethyldiethylenetriamine) has been prepared and reacted in D(2)O with N-acetylmethionine (N-AcMet) and guanosine 5'-monophosphate (5'-GMP); the reactions have been studied using (1)H NMR spectroscopy. Reaction with 5'-GMP leads to two rotamers of [Pt(Me(5)dien)(5'-GMP-N7)](+). Reaction
M Mályusz et al.
Renal physiology and biochemistry, 17(6), 307-315 (1994-11-01)
Hippurate is known to be synthesized from benzoate and glycine in the liver and kidney. It takes part in renal ammoniagenesis by modulating the activity of gamma-glutamyl transpeptidase (gamma GT). Due to its chemical structure, however, hippurate might also serve
Christian Schöneich et al.
Journal of the American Chemical Society, 125(45), 13700-13713 (2003-11-06)
The pathogenesis of Alzheimer's disease is strongly associated with the formation and deposition of beta-amyloid peptide (beta AP) in the brain. This peptide contains a methionine (Met) residue in the C-terminal domain, which is important for its neurotoxicity and its
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