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Merck
CN

06813

α-Boswellic acid

analytical standard

Synonym(s):

(3α,4β)-3-Hydroxyolean-12-en-23-oic acid, 3α-Hydroxyolean-12-en-24-oic acid

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About This Item

Empirical Formula (Hill Notation):
C30H48O3
CAS Number:
471-66-9
Molecular Weight:
456.70
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329748285
MDL number:
MFCD03788779
Beilstein/REAXYS Number:
3074442

Key Documents

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InChI key

BZXULBWGROURAF-IKNLXHIFSA-N

SMILES string

CC1(C)CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@@H](O)[C@@](C)([C@@H]5CC[C@@]34C)C(O)=O)[C@@H]2C1

InChI

1S/C30H48O3/c1-25(2)14-15-26(3)16-17-28(5)19(20(26)18-25)8-9-21-27(4)12-11-23(31)30(7,24(32)33)22(27)10-13-29(21,28)6/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21+,22+,23+,26+,27+,28+,29+,30+/m0/s1

grade

analytical standard

assay

≥95.0% (HPLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

Quality Level

100

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General description

α-Boswellic acid is a pentacyclic triterpene acid belonging to the genus Boswellia. It is a biologically active constituent of Boswellia serrata, known for its anti-inflammatory activity.

Application

α-Boswellic acid may be used as an analytical reference standard for the quantification of the analyte in the following:        
  • Oleogum resins of different Boswellia species using high-performance liquid chromatography with tandem mass spectrometric detection (HPLC-MS/MS).        
  • Frankincense extracts of different Boswellia species using two-dimensional liquid chromatography electrospray ionization tandem mass spectrometry (LC/LC/ESI-MS/MS).

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL7460
BCCK8997
BCCH8851
BCCB1283
BCBW6615

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Comparison Between HPLC and HPTLC Densitometry for the Determination of 11-keto-?-boswellic acid and 3-acetyl-11-keto-?-boswellic acid from Boswellia serrata Extract
Mehta M, et al.
Indian Journal of Pharmaceutical Education and Research, 50(3), 418-423 (2016)
Comparative analysis of pentacyclic triterpenic acid compositions in oleogum resins of different Boswellia species and their in vitro cytotoxicity against treatment-resistant human breast cancer cells
Schmiech M, et al.
Molecules (Basel), 24(11), 2153-2153 (2019)
Analysis of frankincense from various Boswellia species with inhibitory activity on human drug metabolising cytochrome P450 enzymes using liquid chromatography mass spectrometry after automated on-line extraction
Frank A and Unger M
Journal of Chromatography A, 1112(1-2), 255-262 (2006)

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