07270
Methyl 6-aminohexanoate hydrochloride
≥99.0% (AT)
Synonym(s):
Methyl 6-aminocaproate hydrochloride
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About This Item
Linear Formula:
NH2(CH2)5COOCH3 · HCl
CAS Number:
Molecular Weight:
181.66
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3687692
Assay:
≥99.0% (AT)
Form:
powder or crystals
Quality Level
assay
≥99.0% (AT)
form
powder or crystals
reaction suitability
reaction type: solution phase peptide synthesis
color
white
mp
117-124 °C
application(s)
peptide synthesis
SMILES string
Cl.COC(=O)CCCCCN
InChI
1S/C7H15NO2.ClH/c1-10-7(9)5-3-2-4-6-8;/h2-6,8H2,1H3;1H
InChI key
YSLDOTFAFZJPOC-UHFFFAOYSA-N
General description
Methyl 6-aminohexanoate hydrochloride also known as Methyl 6-aminocaproate hydrochloride, is commonly used in the solution-phase peptide synthesis.
Application
Methyl 6-aminohexanoate hydrochloride is used to synthesize papain-catalyzed peptides.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Papain-catalyzed synthesis of polyglutamate containing a nylon monomer unit
K Yazawa
Polymers, 8, 194-194 (2016)
Petr Chytil et al.
Molecular pharmaceutics, 15(9), 3654-3663 (2018-03-16)
Herein, the biodegradable micelle-forming amphiphilic N-(2-hydroxypropyl) methacrylamide (HPMA)-based polymer conjugates with the anticancer drug doxorubicin (Dox) designed for enhanced tumor accumulation were investigated, and the influence of their stability in the bloodstream on biodistribution, namely, tumor uptake, and in vivo
Tomáš Etrych et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 58, 1-12 (2014-03-19)
In this study, we describe the synthesis, physico-chemical characterisation and results of the in vitro and in vivo evaluation of the biological behaviour of N-(2-hydroxypropyl)methacrylamide-based (HPMA) copolymer conjugates bearing doxorubicin (DOX) partly bound via a pH-sensitive hydrazone and partly via
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 07270-25G | 04061832593180 |
| 07270-100G | 04061832593173 |