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15450

Boc-Leu-OH hydrate

≥99.0% (HPLC)

Synonym(s):

Boc-L-leucine

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About This Item

Linear Formula:
(CH3)2CHCH2CH(COOH)NHCOOC(CH3)3 xH2O
Molecular Weight:
231.29 (anhydrous basis)
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
329750886
NACRES:
NA.22
EC Number:
236-073-2
MDL number:
MFCD00066067
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Quality Segment

200

assay

≥99.0% (HPLC)

form

solid

optical activity

[α]20/D −25±0.5°, c = 2% in acetic acid

reaction suitability

reaction type: Boc solid-phase peptide synthesis, reaction type: C-H Activation, reagent type: ligand
reaction type: Peptide Synthesis

mp

85-90 °C

application(s)

peptide synthesis

functional group

amine, carboxylic acid

SMILES string

CC(C)C[C@H](NC(OC(C)(C)C)=O)C(O)=O

InChI

1S/C11H21NO4/c1-7(2)6-8(9(13)14)12-10(15)16-11(3,4)5/h7-8H,6H2,1-5H3,(H,12,15)(H,13,14)/t8-/m0/s1

InChI key

MDXGYYOJGPFFJL-QMMMGPOBSA-N

Application

Boc-protected leucine (Boc-Leu-OH) can be used to generate combinatorial peptide libraries and also to synthesize peptide models to study structure-activity relationships.
Boc-Leu-OH (Boc-L-leucine) was used in the synthesis of a potent cytotoxin, PM-94128.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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