21069
Calcium carbonate
tested according to Ph. Eur.
Synonym(s):
Calcii carbonas
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About This Item
Linear Formula:
CaCO3
CAS Number:
Molecular Weight:
100.09
UNSPSC Code:
12352300
NACRES:
NA.21
PubChem Substance ID:
EC Number:
207-439-9
Beilstein/REAXYS Number:
8008338
MDL number:
Quality Level
agency
tested according to Ph. Eur.
assay
99.3%
form
powder
solubility
1 M acetic acid: soluble, alcohol: insoluble, hydrochloric acid: soluble (3 N), nitric acid: soluble (2 N)
density
2.93 g/mL at 25 °C (lit.)
SMILES string
[Ca++].[O-]C([O-])=O
InChI
1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2
InChI key
VTYYLEPIZMXCLO-UHFFFAOYSA-L
Application
Calcium carbonate has been utilized by plants and animal for the formation of their skeletons and shells. It also facilitates the calcium carbonate crystal growth on a chitosan substrate.
Biochem/physiol Actions
Calcium carbonate is a naturally occurring compound that reduces T4 absorption and enhancess serum thyrotropin levels. It also precludes osteoporosis induced by thyrotropin-suppressive doses of levothyroxine in postmenopausal women. Additionally, it reduces diarrhea in individuals with protease inhibitor-induced HIV-infection.
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Storage Class
13 - Non Combustible Solids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Megan J Turner et al.
HIV clinical trials, 5(1), 19-24 (2004-03-06)
Although some evidence exists to support the practice of using calcium carbonate to treat nelfinavir-induced diarrhea, there is a lack of data supporting the role of calcium in diarrhea induced by other protease inhibitors (PIs). The objective of this prospective
F H Wilt
Journal of structural biology, 126(3), 216-226 (1999-09-04)
The endoskeletal spicules of sea urchin larvae are composed of calcite, a surrounding extracellular matrix, and small amounts of occluded matrix proteins. The spicules are formed by primary mesenchyme cells (PMCs) in the blastocoel of the embryo, where they adopt
N Singh et al.
JAMA, 283(21), 2822-2825 (2000-06-06)
The effect of calcium carbonate on the absorption of levothyroxine has not been studied systematically. Such a potential drug interaction merits investigation because concurrent treatment with both drugs is common, particularly in postmenopausal women. To investigate the potential interference of
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 21069-1KG | 04061838771438 |