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Procyanidin B2

analytical standard

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Synonym(s):
(−)-Epicatechin (4β-8)-(−)-epicatechin, 4,8″-Bi-[(+)-epicatechin], cis,cis″-4,8″-Bi(3,3′,4′,5,7-pentahydroxyflavane), Proanthocyanidin B2
Empirical Formula (Hill Notation):
C30H26O12
CAS Number:
29106-49-8
Molecular Weight:
578.52
MDL number:
MFCD01861513
PubChem Substance ID:
329756197
NACRES:
NA.24

grade

analytical standard

Quality Level

100

Assay

≥90% (HPLC)

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

O[C@@H]1Cc2c(O)cc(O)c([C@@H]3[C@@H](O)[C@H](Oc4cc(O)cc(O)c34)c5ccc(O)c(O)c5)c2O[C@@H]1c6ccc(O)c(O)c6

InChI

1S/C30H26O12/c31-13-7-20(37)24-23(8-13)41-29(12-2-4-16(33)19(36)6-12)27(40)26(24)25-21(38)10-17(34)14-9-22(39)28(42-30(14)25)11-1-3-15(32)18(35)5-11/h1-8,10,22,26-29,31-40H,9H2/t22-,26-,27-,28-,29-/m1/s1

InChI key

XFZJEEAOWLFHDH-NFJBMHMQSA-N

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General description

Procyanidin B2 is a B type of proanthocyanidin, that is present in plants, especially in grape seeds, apples and cacao seeds, which is known to possess anti-inflammatory properties and antioxidant properties.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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T1503
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25G
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705578-5MG-PW

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MMYOMAG-74K-13

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Nabeelah Bibi Sadeer et al.
Journal of pharmaceutical and biomedical analysis, 174, 19-33 (2019-06-04)
Africa is famous for its floral biodiversity, exploited by local people for therapeutic purposes. However, such plants need to be scrutinised scientifically for the presence of bioactive compounds and possible biological properties. This study attempts for the first time to
Absorption and urinary excretion of procyanidin B2 [epicatechin-(4?-8)-epicatechin] in rats
Baba S, et al.
Free Radical Biology & Medicine, 33, 142-148 (2012)
Stavroula Stoupi et al.
Drug metabolism and disposition: the biological fate of chemicals, 38(2), 287-291 (2009-11-17)
Procyanidins are important biologically active compounds, but the pathway and extent of absorption and metabolism are controversial. We conducted a mass balance study to evaluate the total radioactivity excreted in urine and feces after oral administration of [(14)C]procyanidin B2 to
Javier I Ottaviani et al.
The American journal of clinical nutrition, 95(4), 851-858 (2012-03-02)
Accumulating data show a causal role for flavanols in the mediation of cardiovascular benefits associated with the consumption of flavanol- and procyanidin-containing foods. Evidence for a direct causal role for procyanidins in this context is far less profound due to
Procyanidin B2 gallates inhibit IFN-? and IL-17 production in T cells by suppressing T-bet and ROR?t expression
Tanaka S, et al.
International Immunopharmacology, 44, 87-96 (2017)
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