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43016

Ginsenoside Rg5

analytical standard

Synonym(s):

(3β, 12β,20E)-12-Hydroxydammara-20(22),24-dien-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

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About This Item

Empirical Formula (Hill Notation):
C42H70O12
CAS Number:
186763-78-0
Molecular Weight:
767.00
MDL number:
MFCD22200429
UNSPSC Code:
85151701
NACRES:
NA.24
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grade

analytical standard

Quality Level

100

assay

≥90.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

application(s)

food and beverages

format

neat

storage temp.

2-8°C

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O)CO)O[C@@H]3C([C@H]4[C@@]([C@@H]5[C@]([C@]6([C@H]([C@@H](C5)O)[C@H](CC6)\C(=C\CC=C(C)C)\C)C)(CC4)C)(CC3)C)(C)C

InChI

1S/C42H70O12/c1-21(2)10-9-11-22(3)23-12-16-42(8)30(23)24(45)18-28-40(6)15-14-29(39(4,5)27(40)13-17-41(28,42)7)53-38-36(34(49)32(47)26(20-44)52-38)54-37-35(50)33(48)31(46)25(19-43)51-37/h10-11,23-38,43-50H,9,12-20H2,1-8H3/b22-11+/t23-,24-,25-,26-,27+,28-,2

InChI key

NJUXRKMKOFXMRX-RNCAKNGISA-N

General description

Ginsenoside Rg5 is a diol-containing ginsenoside, that occurs naturally in Panax ginseng. It is found to be a promising agent in the treatment of Alzheimer′s disease.

Application

Ginsenoside Rg5 may be used as a reference standard in the determination of ginsenoside Rg5 in Korean red ginseng using high performance liquid chromatography coupled with evaporative light scattering detection (HPLC-ELSD).

Other Notes

This compound is commonly found in plants of the genus: panax

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCP4367
BCCK9922
BCCG5553
BCCF8045
BCCD3557

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Ginsenoside-Rg5 suppresses cyclin E-dependent protein kinase activity via up-regulating p21Cip/WAF1 and down-regulating cyclin E in SK-HEP-1 cells.
K Y L, et al.
Anticancer Research, 17(2A), 1067-1072 (1997)
Inhibitory effect of ginsenoside Rg5 and its metabolite ginsenoside Rh3 in an oxazolone-induced mouse chronic dermatitis model.
Shin W-Y, et al.
Archives of Pharmacal Research, 29(8), 685-690 (2006)
Ginsenoside Rg5 improves cognitive dysfunction and beta-amyloid deposition in STZ-induced memory impaired rats via attenuating neuroinflammatory responses.
Chu S, et al.
International Journal of Immunopharmacology, 19(2), 317-326 (2014)
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Global Trade Item Number

SKUGTIN
43016-5MG04061832107837