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Merck
CN

55608

Vitexin 2-O-rhamnoside

analytical standard

Synonym(s):

2-O-Rhamnosylvitexin

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About This Item

Empirical Formula (Hill Notation):
C27H30O14
CAS Number:
Molecular Weight:
578.52
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
Technical Service
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grade

analytical standard

Quality Level

assay

≥98.0% (TLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2c3c(O)cc(O)c4C(=O)C=C(Oc34)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C27H30O14/c1-9-19(33)21(35)23(37)27(38-9)41-26-22(36)20(34)16(8-28)40-25(26)18-13(31)6-12(30)17-14(32)7-15(39-24(17)18)10-2-4-11(29)5-3-10/h2-7,9,16,19-23,25-31,33-37H,8H2,1H3/t9-,16+,19-,20+,21+,22-,23+,25-,26+,27-/m0/s1

InChI key

LYGPBZVKGHHTIE-HUBYJIGHSA-N

General description

Vitexin 2-O-rhamnoside is an active component of hawthorn, a member of the Rosaceae family, exhibits a broad-spectrum of pharmacological properties such as anti-inflammatory, sedative, anti-arrhythmia, effectively inhibiting lipid oxidation, decreasing blood pressure and serum levels of cholesterol, improving digestion and relieving food stasis, etc.

Application

Vitexin 2-O-rhamnoside may be used as an analytical reference standard for the quantification of the analyte in hawthorn leaves, fruits and plasma samples using various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Other Notes

This compound is commonly found in plants of the genus: crataegus


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Validation and application by HPLC for simultaneous determination of vitexin-2 ?-O-glucoside, vitexin-2 ?-O-rhamnoside, rutin, vitexin, and hyperoside
Wang H-C, et al.
Journal of Pharmaceutical Analysis, 1(4), 291-296 (2011)
Determination of vitexin-2 ?-O-rhamnoside in rat plasma by ultra-performance liquid chromatography electrospray ionization tandem mass spectrometry and its application to pharmacokinetic study
Ying X, et al.
Talanta, 72(4), 1500-1506 (2007)
Anne Pick et al.
Bioorganic & medicinal chemistry, 19(6), 2090-2102 (2011-03-01)
Flavonoids are an interesting group of natural products ubiquitously present in human diet. Their consumption has been associated with various and differing beneficial health effects. However, several flavonoids have been reported to inhibit the breast cancer resistance protein (BCRP) encoded



Global Trade Item Number

SKUGTIN
55608-5MG-F04061832582641
55608-25MG-F04061833277638