Skip to Content
Merck
CN

Key Documents

View All Documentation

68790

Drometrizole trisiloxane

analytical standard

Synonym(s):

2-(2H-Benzotriazol-2-yl)-4-methyl-6-{2-methyl-3-{1,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl}propyl}phenol, Silatrizole

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C24H39N3O3Si3
CAS Number:
155633-54-8
Molecular Weight:
501.84
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
329760825
MDL number:
MFCD22373626
Beilstein/REAXYS Number:
11343300
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

analytical standard

Quality Level

100

assay

≥98.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

SMILES string

CC(Cc1cc(C)cc(c1O)-n2nc3ccccc3n2)C[Si](C)(O[Si](C)(C)C)O[Si](C)(C)C

InChI

1S/C24H39N3O3Si3/c1-18-14-20(15-19(2)17-33(9,29-31(3,4)5)30-32(6,7)8)24(28)23(16-18)27-25-21-12-10-11-13-22(21)26-27/h10-14,16,19,28H,15,17H2,1-9H3

InChI key

HUVYTMDMDZRHBN-UHFFFAOYSA-N

General description

Drometrizole trisiloxane (DRT) belongs to the lipophilic benzotriazole derivative class of compounds commonly utilized in sunscreen cosmetics.

Application

DRT may be used as a reference standard for the determination of DRT in:
  • Active pharmaceutical ingredients (APIs), formulations and stability samples by reversed phase ultra-high performance liquid chromatography (RP-UPLC) coupled to electrospray ionization-quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS).
  • Suncare formulations by high performance liquid chromatography (HPLC) with ultraviolet (UV) detection.
  • Cosmetic products by LC-UV.
  • Sewage sludge samples by QuEChERS (quick, easy, cheap, effective, rugged, and safe) extraction procedure and gas chromatography combined with MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Still not finding the right product?

Explore all of our products under Drometrizole trisiloxane

hcodes

H413

Hazard Classifications

Aquatic Chronic 4

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCM6795
BCCH9053
BCCD0345
BCBV5651
BCBS1141V

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A Sensitive, Stability indicating UPLC method for the identification and characterization of forced degradation products for Drometrizole Trisiloxane through MSn studies.
Babu MA, et al.
Journal of Applied Pharmaceutical Science, 8(06), 065-074 (2018)
A reliable and environmentally-friendly liquid-chromatographic method for multi-class determination of fat-soluble UV filters in cosmetic products.
Chisvert A, et al.
Analytica Chimica Acta, 790(1-2), 61-67 (2013)
Development and optimization of a QuEChERS-GC-MS/MS methodology to analyse ultraviolet-filters and synthetic musks in sewage sludge.
Ramos S, et al.
The Science of the Total Environment, 790(1-2), 61-67 (2018)
View All Related Papers

Global Trade Item Number

SKUGTIN
68790-50MG04061832764627