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Merck
CN

68909

Sennoside A

analytical standard

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About This Item

Empirical Formula (Hill Notation):
C42H38O20
CAS Number:
Molecular Weight:
862.74
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
EC Number:
201-339-9
Beilstein/REAXYS Number:
5723746
MDL number:
Technical Service
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grade

analytical standard

Quality Segment

assay

≥96.0% (HPLC)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

SMILES string

OC[C@H]1O[C@@H](Oc2cccc3[C@@H]([C@@H]4c5cccc(O[C@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c7c(O)cc(cc47)C(O)=O)c8cc(cc(O)c8C(=O)c23)C(O)=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26-,31-,32-,35+,36+,37-,38-,41-,42?/m1/s1

InChI key

IPQVTOJGNYVQEO-GTCVFCFLSA-N

General description

Sennoside A is a hydroxy anthracene glycoside generally present in the polyherbal formulations that contain Cassia angustifolia leaves, which is used in the treatment of constipation.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Status of sennosides content in various Indian herbal formulations: method standardization by HPTLC
Aktar W, et al.
Bangladesh Journal of Pharmacology, 3, 64-68 (2008)
Jing Xiao et al.
Wei sheng yan jiu = Journal of hygiene research, 40(3), 355-357 (2011-06-24)
To develop an analytical method for determination of sennoside A and sennoside B simultaneously in health food by high performance liquid chromatography (HPLC). Samples were extracted by ultrasound extraction and determined by HPLC with a UV detector. Using a Synergi
Emi Matsui et al.
Biological & pharmaceutical bulletin, 34(9), 1438-1442 (2011-09-02)
Daiokanzoto (DKT), a Kampo medicine that includes the combination of two crude drugs (rhubarb and glycyrrhiza), is clinically effective for constipation. The aim of this study is to clarify the influence of glycyrrhiza, three glycyrrhiza constituents (glycyrrhizin, liquiritin, and liquiritin



Global Trade Item Number

SKUGTIN
68909-25MG-F04061832764849
68909-5MG-F04061832764856