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Merck
CN

69545

Kaempferide

analytical standard

Synonym(s):

3,5,7-Trihydroxy-4′-methoxyflavone, KF, 4′-Methoxy-3,5,7-trihydroxyflavone

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About This Item

Empirical Formula (Hill Notation):
C16H12O6
CAS Number:
491-54-3
Molecular Weight:
300.26
UNSPSC Code:
85151701
NACRES:
NA.24
PubChem Substance ID:
329761743
EC Number:
207-738-4
Beilstein/REAXYS Number:
305378
MDL number:
MFCD00016771

Key Documents

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Product Name

Kaempferide, analytical standard

InChI key

SQFSKOYWJBQGKQ-UHFFFAOYSA-N

InChI

1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3

SMILES string

COc1ccc(cc1)C2=C(O)C(=O)c3c(O)cc(O)cc3O2

grade

analytical standard

assay

≥99.0% (HPLC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

2-8°C

Quality Level

100

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Application

Kaempferide may be used as an analytical reference standard for the quantification of the analyte in propolis and traditional Chinese medicine Zuo Gui Wan using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Kaempferide is a naturally occurring, O-methylated flavonol found in Kaempferia galanga. It exhibits a variety of pharmacological effects such as anti-inflammatory, anti-viral, anti-oxidant, anti-bacterial and antitumor properties.

Other Notes

This compound is commonly found in plants of the genus: arnica silybum

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
BCCM2872
BCCJ6752
BCCG2636
BCCB6186
BCBX5292

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Madoka Takashima et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 132, 110669-110669 (2019-07-13)
Propolis is a sticky dark-colored substance produced by honey bees and comprises resin, balsam, wax, essential and aromatic oils, pollen, and several other substances; it is used in food and beverages to improve health and prevent diseases. We studied the
Ehab Ghazy et al.
European journal of medicinal chemistry, 200, 112338-112338 (2020-06-05)
Histone modifying proteins, specifically histone deacetylases (HDACs) and bromodomains, have emerged as novel promising targets for anticancer therapy. In the current work, based on available crystal structures and docking studies, we designed dual inhibitors of both HDAC6/8 and the bromodomain
Selective analysis of phenolic compounds in propolis by HPLC?MS/MS
Medana C, et al.
Phytochemical Analysis, 19(1), 32-39 (2008)
Kaempferide prevents titanium particle induced osteolysis by suppressing JNK activation during osteoclast formation
Jiao Z, et al.
Scientific Reports, 7(1) (2017)
Cuiping Zhang et al.
Journal of food science, 82(7), 1602-1607 (2017-06-01)
Brazilian green propolis is known as an appreciable natural antioxidant with abundant polyphenolic compounds. For quality control, a fingerprint-efficacy study of Brazilian green propolis was carried out in this work. Chemical fingerprints of Brazilian green propolis from 22 different sources
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