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Resveratrol

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

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Synonym(s):
3,4′,5-Trihydroxy-trans-stilbene, 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3-benzenediol
Empirical Formula (Hill Notation):
C14H12O3
CAS Number:
501-36-0
Molecular Weight:
228.24
MDL number:
MFCD00133799
PubChem Substance ID:
329767153
NACRES:
NA.24

grade

certified reference material
TraceCERT®

Quality Level

300

product line

TraceCERT®

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

food and beverages

format

neat

storage temp.

−20°C

SMILES string

Oc1ccc(cc1)\C=C\c2cc(O)cc(O)c2

InChI

1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+

InChI key

LUKBXSAWLPMMSZ-OWOJBTEDSA-N

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General description

Resveratrol (RV) is a polyphenol nonflavonoid compound mainly found in grapes and red wine and also in some strong pigmented fruits and vegetables that exhibits antitumor, antioxidant, antiviral, and phytoestrogenic biological activities.
This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Resveratrol (RV) has been used as a reference standard for the determination of trans- and cis-resveratrol in wine by capillary electrophoresis method.
Selective inhibitor of COX−1.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Legal Information

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319

Hazard Classifications

Eye Irrit. 2

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

392.0 °F - closed cup - (External MSDS)

Flash Point(C)

> 200.0 °C - closed cup - (External MSDS)

Certificates of Analysis (COA)

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Multiplicity of effects and health benefits of resveratrol.
Kursvietien? L, et al.
Medicina (Kaunas, Lithuania), 52(3), 148-155 (2016)
Capillary electrophoresis analysis of trans-and cis-resveratrol, quercetin, catechin and gallic acid in wine.
Prasongsidh B C, et al.
Food Chemistry, 62(3), 355-358 (1998)
Therapeutic potential of resveratrol: the in vivo evidence.
Baur JA, et al.
Nature Reviews. Drug Discovery, 5(6), 493-493 (2006)
Timothy M Bass et al.
Mechanisms of ageing and development, 128(10), 546-552 (2007-09-19)
It was recently reported that the plant polyphenol resveratrol, found, e.g., in grape berry skins, extended lifespan in the fruit fly Drosophila melanogaster and the nematode worm Caenorhabditis elegans. This lifespan extension was dependent on an NAD(+)-dependent histone deacetylase, Sir2
Satya Dash et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(12), 2895-2901 (2013-09-28)
Overproduction of hepatic apolipoprotein B (apoB)-100 containing very low-density lipoprotein particles and intestinal apoB-48 containing chylomicrons contributes to hypertriglyceridemia seen in conditions such as obesity and insulin resistance. Some, but not all, preclinical and clinical studies have demonstrated that the
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