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BP802

Lamivudine

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

2′,3′-Dideoxy-3′-thiacytidine, 3TC, Epivir, Epivir-HBV, Heptovir, Zeffix

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About This Item

Empirical Formula (Hill Notation):
C8H11N3O3S
CAS Number:
134678-17-4
Molecular Weight:
229.26
UNSPSC Code:
41116107
NACRES:
NA.24
MDL number:
MFCD00869739
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grade

pharmaceutical primary standard

API family

lamivudine

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

SMILES string

NC1=NC(=O)N(C=C1)[C@@H]2CS[C@H](CO)O2

InChI

1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1

InChI key

JTEGQNOMFQHVDC-NKWVEPMBSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lamivudine BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Abacavir, Zidovudine and Lamivudine Tablets
  • Zidovudine and Lamivudine Tablets
  • Abacavir and Lamivudine Tablets
  • Lamivudine Tablets

    • Biochem/physiol Actions

    Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).
    Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is an analogue of cytidine, and can inhibit both types (1 and 2) of HIV reverse transcriptase as well as the reverse transcriptase of hepatitis B. It needs to be phosphorylated to its triphosphate form before it is active. 3TC-triphosphate also inhibits cellular DNA polymerase.

    Packaging

    Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    Other Notes

    Sales restrictions may apply.

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    pictograms

    Health hazard
    GHS08

    signalword

    Warning

    Storage Class

    11 - Combustible Solids

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    target_organs

    Blood

    Hazard Classifications

    Aquatic Chronic 3 - Repr. 2 - STOT RE 2

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    Global Trade Item Number

    SKUGTIN
    BP80204061835277650