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D2922000

Disopyramide phosphate

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Disopyramide phosphate salt, α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide

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About This Item

Linear Formula:
C21H29N3O · H3PO4
CAS Number:
22059-60-5
Molecular Weight:
437.47
NACRES:
NA.24
PubChem Substance ID:
329798760
UNSPSC Code:
41116107
MDL number:
MFCD00069254
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grade

pharmaceutical primary standard

API family

disopyramide

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

OP(O)(O)=O.CC(C)N(CCC(C(N)=O)(c1ccccc1)c2ccccn2)C(C)C

InChI

1S/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(H3,1,2,3,4)

InChI key

CGDDQFMPGMYYQP-UHFFFAOYSA-N

Gene Information

human ... SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Disopyramide phosphate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem/physiol Actions

Class IA antiarrhythmic; sodium channel blocker

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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[Disopyramide phosphate: the electrophysiological mechanisms of its anti-arrhythmia action and its use in clinical practice].
A A Grosu
Kardiologiia, 25(5), 114-118 (1985-05-01)
R Di Bianco et al.
Angiology, 38(2 Pt 2), 174-183 (1987-02-01)
In the absence of preexistent myocardial dysfunction, the risk of producing cardiac decompensation in patients being treated with any of the conventional antiarrhythmic agents is low. The availability of disopyramide for clinical use in 1977 produced optimism for an effective

Global Trade Item Number

SKUGTIN
D292200004061833562710