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F0060000

Fenticonazole nitrate

Name: Fenticonazole nitrate
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):

C₂₄H₂₁Cl₂N₃O₄S

CAS Number:

73151-29-8

Molecular Weight:

518.41

MDL number:

MFCD00941391

UNSPSC Code:

41116107

NACRES:

NA.24

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Properties

grade

pharmaceutical primary standard

API family

fenticonazole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

S(c2ccc(cc2)COC(C[n]4cncc4)c3c(cc(cc3)Cl)Cl)c1ccccc1.[N+](=O)([O-])O

InChI

1S/C24H20Cl2N2OS.HNO3/c25-19-8-11-22(23(26)14-19)24(15-28-13-12-27-17-28)29-16-18-6-9-21(10-7-18)30-20-4-2-1-3-5-20;2-1(3)4/h1-14,17,24H,15-16H2;(H,2,3,4)

InChI key

FJNRUWDGCVDXLU-UHFFFAOYSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Fenticonazole nitrate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

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Antifungal topical therapy in oral chronic candidosis. A comparative study.

Silvia Adriana Lopez-De-Blanc et al.

Medicina oral : organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal, 7(4), 260-270 (2002-07-23)

The aim of the present paper was to evaluate the effect of fenticonazole and to compare it with that of ketoconazole and nystatin in the topical treatment of oral chronic candidosis. Eighty patients diagnosed with erythematous chronic candidosis were divided

Topical fenticonazole in dermatology and gynaecology: current role in therapy.

Stefano Veraldi et al.

Drugs, 68(15), 2183-2194 (2008-10-09)

Fenticonazole is an imidazole derivative with a broad spectrum of antimycotic activity against dermatophytes and yeasts in in vitro and clinical studies. Fenticonazole exerts its unique antimycotic mechanism of action in the following three ways: (i) inhibition of the secretion

Fenticonazole nitrate for treatment of vulvovaginitis: efficacy, safety, and tolerability of 1-gram ovules, administered as ultra-short 2-day regimen.

J Fernández-Alba et al.

Journal of chemotherapy (Florence, Italy), 16(2), 179-186 (2004-06-26)

Because of its potential as a low cost first-line monotherapy for the most common vulvovaginal infections, we evaluated fenticonazole nitrate in a prospective, open-label, multicenter pilot study with 101 sexually active women (per-protocol; 16 to 61 years of age) with

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Global Trade Item Number

SKU	GTIN
F0060000	04061833610732