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F0918

Fura-2 LeakRes (AM)

≥85%

Synonym(s):

Fura PE 3-AM

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About This Item

Empirical Formula (Hill Notation):
C55H63N5O29
CAS Number:
172890-84-5
Molecular Weight:
1258.10
UNSPSC Code:
12171500
PubChem Substance ID:
24894737
MDL number:
MFCD00285848
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Quality Level

200

assay

≥85%

storage temp.

−20°C

SMILES string

CC(=O)OCOC(=O)CN1CCN(CC1)C(=O)CCc2ccc(N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)c(OCCOc3cc4cc(oc4cc3N(CC(=O)OCOC(C)=O)CC(=O)OCOC(C)=O)-c5ncc(o5)C(=O)OCOC(C)=O)c2

InChI

1S/C55H63N5O29/c1-33(61)76-27-82-49(68)22-57-11-13-58(14-12-57)48(67)10-8-39-7-9-41(59(23-50(69)83-28-77-34(2)62)24-51(70)84-29-78-35(3)63)44(17-39)74-15-16-75-45-18-40-19-46(54-56-21-47(89-54)55(73)87-32-81-38(6)66)88-43(40)20-42(45)60(25-52(71)85-30-79-36(4)64)26-53(72)86-31-80-37(5)65/h7,9,17-21H,8,10-16,22-32H2,1-6H3

InChI key

CGAZNAYDEAJZHQ-UHFFFAOYSA-N

General description

Fura-2 LeakRes (AM) is a cell permeable fluorescent probe for Ca2+. Compared with other probes, there is less compartmentalization and leakage; cells remain brightly fluorescent and responsive to changes in cytosolic free Ca2+ for hours.

Application

Fura-2 LeakRes (AM) has been used for imaging of intracellular Ca2+.
Fura 2 is one of the most widely used calcium indicators for ratiometric measurement and is highly suitable for digital imaging microscopy.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
SLBS7163
SLBS9979
SLBT0176
SLBQ7936V
SLBN0116V

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RNA interference screening in Drosophila primary cells for genes involved in muscle assembly and maintenance.
Bai J
Development, 135, 1439-1439 (2008)
M W Roe et al.
Cell calcium, 11(2-3), 63-73 (1990-02-01)
Fura-2 has become the most popular fluorescent probe with which to monitor dynamic changes in cytosolic free calcium in intact living cells. In this paper, we describe many of the currently recognized limitations to the use of Fura-2 in living

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