G0750
D-(+)-Galactose
≥99% (HPLC)
Synonym(s):
Galactose
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About This Item
Empirical Formula (Hill Notation):
C6H12O6
CAS Number:
Molecular Weight:
180.16
UNSPSC Code:
12352201
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-416-4
Beilstein/REAXYS Number:
1724619
MDL number:
biological source
bovine (Ruminant- Cow, Ox, Buffalo)
Quality Level
assay
≥99% (HPLC)
form
powder
technique(s)
HPLC: suitable
impurities
≤0.1% glucose
color
white
useful pH range
5.0-7 (25 °C, 180 g/L)
mp
168-170 °C (lit.)
solubility
H2O: soluble 100 mg/mL, clear, colorless
storage temp.
room temp
SMILES string
OC[C@@H](O)[C@H](O)[C@H](O)[C@@H](O)C=O
InChI
1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6-/m0/s1
InChI key
GZCGUPFRVQAUEE-KCDKBNATSA-N
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Application
Galactose has been used:
- as a component of galactosyltransferase labeling buffer.
- as a supplement in MRS broth for the growth of thermophilic lactobacilli
- to induce the expression of uncoupling protein (UCP) in yeast transformants
Biochem/physiol Actions
Galactose is a simple monosaccharide that serves as an energy source and as an essential component of glycolipids and glycoproteins. Galactose contributes to energy metabolism via its conversion to glucose by the enzymes that constitute the Leloir pathway. Defects in the genes encoding these proteins lead to the metabolic disorder galactosemia.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
涉药品监管产品
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D L Murdza-Inglis et al.
The Journal of biological chemistry, 269(10), 7435-7438 (1994-03-11)
The uncoupling protein is one of a family of mitochondrial transport proteins involved in energy metabolism. It dissipates oxidative energy to generate heat, either by catalyzing proton transport directly or by catalyzing fatty acid anion transport, thus enabling fatty acids
K W Turner et al.
Applied and environmental microbiology, 45(6), 1932-1934 (1983-06-01)
The ability to ferment galactose is a major characteristic which can be used to differentiate Lactobacillus helveticus (galactose positive) from Lactobacillus lactis and Lactobacillus bulgaricus (galactose negative). In milk cultures, galactose-positive strains produced d- and l-lactic acid with little galactose
Zu-Hong He et al.
Redox biology, 28, 101364-101364 (2019-11-16)
Inflammation is a self-defense response to protect individuals from infection and tissue damage, but excessive or persistent inflammation can have adverse effects on cell survival. Many individuals become especially susceptible to chronic-inflammation-induced sensorineural hearing loss as they age, but the
Hwa-Young Lee et al.
Redox biology, 37, 101727-101727 (2020-10-04)
Oxidative stress attributable to the activation of a Nox4-containing NADPH oxidase is involved in aging-associated vascular dysfunction. However, the Nox4-induced signaling mechanism for the vascular alteration in aging remains unclear. In an aged aorta, the expression of Nox4 mRNA and
Inge E Krabbendam et al.
Cell death & disease, 11(4), 263-263 (2020-04-25)
Metabolic flexibility is an essential characteristic of eukaryotic cells in order to adapt to physiological and environmental changes. Especially in mammalian cells, the metabolic switch from mitochondrial respiration to aerobic glycolysis provides flexibility to sustain cellular energy in pathophysiological conditions.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| G0750-1KG | 04061835366705 |
| G0750-5G | 04061833624135 |
| G0750-100G | 04061835366682 |
| G0750-10MG | 04061833624128 |
| G0750-10G | 04061835366699 |
| G0750-500G | 04061835366729 |
| G0750-25G | 04061835366712 |
| G0750-50G | 04061835366736 |
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