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About This Item
Empirical Formula (Hill Notation):
C16H21NO3 · HBr
CAS Number:
Molecular Weight:
356.25
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
pharmaceutical primary standard
API family
homatropine
manufacturer/tradename
EDQM
mp
214-217 °C (lit.)
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
Br.CN1C2CCC1CC(C2)OC(=O)C(O)c3ccccc3
InChI
1S/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H
InChI key
DWSGTFTVBLXELC-UHFFFAOYSA-N
General description
Homatropine hydrobromide is an anticholinergic agent and is commonly used as a mydriatic and cycloplegic drug in ophthalmology.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
This European Pharmacopoeia reference standard is intended for use only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
监管及禁止进口产品
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Sean M Bryant et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2(4), 156-159 (2007-12-12)
Most hospitals lack a sufficient supply of atropine to treat, simultaneously, patients poisoned with multiple organophosphorous compound (OC) or nerve agent. The presence of a ubiquitous alternate antidote would prove useful if mass poisoning occurred. Our objective was to evaluate
N George et al.
Autonomic & autacoid pharmacology, 30(3), 173-177 (2010-01-21)
This study investigated whether four anticholinergics which are not clinically used for relaxing the urinary bladder detrusor muscle inhibit the contraction of isolated caprine (goat) detrusor muscle: cyclopentolate (100 nm), homatropine (5 microm), ipratropium (500 nm) and valethamate (1 microm).
Topical chloramphenicol prophylaxis is of dubious benefit in corneal abrasion.
Joseph Ting
Emergency medicine Australasia : EMA, 23(2), 231-231 (2011-04-15)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| H0800000 | 04061833811412 |