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Merck
CN

L5750

Sodium dodecyl sulfate

greener alternative

92.5-100.5% based on total alkyl sulfate content basis

Synonym(s):

Dodecyl sodium sulfate, Dodecyl sulfate sodium salt, Lauryl sulfate sodium salt, SDS, Sodium lauryl sulfate

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About This Item

Linear Formula:
CH3(CH2)11OSO3Na
CAS Number:
151-21-3
Molecular Weight:
288.38
NACRES:
NA.21
PubChem Substance ID:
24896412
eCl@ss:
39093306
UNSPSC Code:
12161900
EC Number:
205-788-1
MDL number:
MFCD00036175
Beilstein/REAXYS Number:
3599286

Key Documents

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description

anionic

Quality Level

200

assay

92.5-100.5% based on total alkyl sulfate content basis

mol wt

288.38 g/mol

greener alternative product characteristics

Catalysis
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sustainability

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aggregation number

62

technique(s)

: suitable using [cell culture | mammalian: suitable]

CMC

7-10 mM (20-25°C)

mp

204-207 °C (lit.)

transition temp

cloud point >100 °C

solubility

water: soluble

HLB

40

application(s)

(Western Blot)

greener alternative category

Aligned

SMILES string

[Na+].CCCCCCCCCCCCOS([O-])(=O)=O

InChI

1S/C12H26O4S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15;/h2-12H2,1H3,(H,13,14,15);/q;+1/p-1

InChI key

DBMJMQXJHONAFJ-UHFFFAOYSA-M

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General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is used as a surfactant to enhance catalysis.  Click here for more information.

Application

Sodium dodecyl sulfate has been used:
  • to dissolve insoluble purple formazan in 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay
  • to perform SDS–PAGE of yeast tubulin
  • as an additive in linolenic acid solution to assess the total antioxidative activity (TAA) of the bacteria using the linolenic acid test (LA-test)

Anionic detergent

Biochem/physiol Actions

Sodium dodecyl sulfate (SDS)/lauryl sulfate, an ionic detergent has the ability to distract biological membranes. It can block RNase and deoxyribonuclease (DNase) activity. SDS is one of the main constituents of several reagents, that are used to purify nucleic acids. It is also considered as a permeability enhancer in oral formulations.

Analysis Note

Actual composition given on label
Predominantly (approx. 70%) C12; lauryl sulfate, sodium salt; balance consists of higher homologs.

signalword

Danger

flash_point_f

338.0 °F

flash_point_c

170 °C

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Flam. Sol. 2 - Skin Irrit. 2

Storage Class

4.1B - Flammable solid hazardous materials

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Certificates of Analysis (COA)

Lot/Batch Number
0000540283
0000540282
0000540281
0000540456
0000540283

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Resilient Ribonucleases
RNA Methodologies (2010)
The two alpha-tubulin isotypes in budding yeast have opposing effects on microtubule dynamics in vitro
Bode CJ, et al.
EMBO Reports, 4(1), 94-99 (2003)
Two antioxidative lactobacilli strains as promising probiotics
Kullisaar T, et al.
International Journal of Food Microbiology, 72(3), 215-224 (2002)
Safety and efficacy of self-assembling bubble carriers stabilized with sodium dodecyl sulfate for oral delivery of therapeutic proteins
Lin P Y, et al.
Journal of Controlled Release : Official Journal of the Controlled Release Society, 259, 168-175 (2017)
Ursolic, oleanolic and betulinic acids: antibacterial spectra and selectivity indexes.
Fontanay S, et al.
Journal of Ethnopharmacology, 120(2), 272-276 (2008)
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Global Trade Item Number

SKUGTIN
L5750-100G04061835546480
L5750-500G04061835546503
L5750-1KG04061835546497
L5750-5KG04061833958360

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