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Merck
CN

M0600900

Metamizole sodium

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Dipyrone monohydrate

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About This Item

Empirical Formula (Hill Notation):
C13H16N3NaO4S · H2O
CAS Number:
Molecular Weight:
351.35
UNSPSC Code:
41116107
NACRES:
NA.24
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grade

pharmaceutical primary standard

API family

metamizole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

[Na+].[S](=O)(=O)([O-])CN(C)c1[c]([n]([n](c1C)C)c2ccccc2)=O.O

InChI

1S/C13H17N3O4S.Na.H2O/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;;/h4-8H,9H2,1-3H3,(H,18,19,20);;1H2/q;+1;/p-1

InChI key

UNZIDPIPYUMVPA-UHFFFAOYSA-M

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Metamizole sodium EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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pictograms

Health hazard

signalword

Warning

hcodes

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品

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C G Manole et al.
Journal of cellular and molecular medicine, 15(11), 2284-2296 (2011-09-08)
We used rat experimental myocardial infarction to study the ultrastructural recovery, especially neo-angiogenesis in the infarction border zone. We were interested in the possible role(s) of telocytes (TCs), a novel type of interstitial cell very recently discovered in myocardim (see
Update on the incidence of metamizole sodium-induced blood dyscrasias in Poland.
Basak G W, et al.
The Journal of International Medical Research, 38(4), 1374-1380 (2010)
Acute kidney injury associated with metamizole sodium ingestion.
Hassan K, et al.
Renal Failure, 33(5), 544-547 (2011)



Global Trade Item Number

SKUGTIN
M060090004061833993422