M4126
5-Methoxytryptophol
analytical standard
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About This Item
Empirical Formula (Hill Notation):
C11H13NO2
CAS Number:
Molecular Weight:
191.23
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
211-919-3
MDL number:
grade
analytical standard
Quality Level
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
forensics and toxicology
pharmaceutical (small molecule)
veterinary
format
neat
storage temp.
2-8°C
SMILES string
COc1ccc2[nH]cc(CCO)c2c1
InChI
1S/C11H13NO2/c1-14-9-2-3-11-10(6-9)8(4-5-13)7-12-11/h2-3,6-7,12-13H,4-5H2,1H3
InChI key
QLWKTGDEPLRFAT-UHFFFAOYSA-N
Application
5-Methoxytryptophol may be used as an analytical reference standard for the quantification of the analyte in biological samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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J B Zawilska et al.
Journal of pineal research, 29(1), 1-7 (2000-08-19)
In the chick pineal gland, 5-methoxytryptophol and melatonin concentrations fluctuate in a rhythmic manner. These rhythms are circadian in nature persisting in constant darkness and have opposite phases. Acute exposure of chicks to white light (30 lux for 5, 10
E B Naranjo-Rodriguez et al.
Progress in neuro-psychopharmacology & biological psychiatry, 24(1), 117-129 (2000-02-05)
Male Wistar rats (120-230 g) were used in these experiments. Some rats were deprived of water for 48 h before testing in a conflict procedure. Then, after 20 licks from a water bottle with a metal drinking tube, the animal
J J García et al.
Journal of cellular biochemistry, 76(4), 651-657 (2000-02-02)
Lipid peroxidation is a degenerative chain reaction in biological membranes that may be initiated by exposure to free radicals. This process is associated with changes in the membrane fluidity and loss of several cell membrane-dependent functions. 5-methoxytryptophol (ML) is an
H Wang et al.
Pharmacology & toxicology, 86(3), 125-128 (2001-02-07)
Injection of the pineal indoles melatonin, 5-methoxytryptophol and 5-methoxytryptamine via the external jugular vein elicited a dose-dependent depression in mean arterial pressure. Melatonin and 5-methoxytryptophol were approximately equipotent and a dose of 150 micromol/kg brought about a reduction of about
Determination of 5-methoxyindoles in pineal gland and plasma samples by high-performance liquid chromatography with electrochemical detection
Melatonin and the Mammalian Pineal Gland, 564(1), 103-113 (1994)
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