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O5015

Oxybutynin chloride

Name: Oxybutynin chloride
Brand: SIAL

meets EP, USP testing specifications

Synonym(s):

α-Phenylcyclohexaneglycolic acid 4-(diethylamino)-2-butynyl ester hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₂₂H₃₁NO₃ · HCl

CAS Number:

1508-65-2

Molecular Weight:

393.95

NACRES:

NA.21

PubChem Substance ID:

24898008

UNSPSC Code:

12161900

EC Number:

216-139-7

MDL number:

MFCD00072150

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Properties

Quality Segment

200

agency

USP/NF, meets EP testing specifications, meets USP testing specifications

form

solid

application(s)

pharmaceutical (small molecule)

storage temp.

room temp

SMILES string

Cl.CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c2ccccc2

InChI

1S/C22H31NO3.ClH/c1-3-23(4-2)17-11-12-18-26-21(24)22(25,19-13-7-5-8-14-19)20-15-9-6-10-16-20;/h5,7-8,13-14,20,25H,3-4,6,9-10,15-18H2,1-2H3;1H

InChI key

SWIJYDAEGSIQPZ-UHFFFAOYSA-N

Gene Information

human ... CHRM2(1129), CHRM3(1131)

Description

Biochem/physiol Actions

Muscarinic acetylcholine receptor antagonist.

Muscarinic acetylcholine receptor antagonist; inhibits proliferation of bladder smooth muscle cells, perhaps by downregulation of growth promoting genes.

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pictograms

GHS07

signalword

Warning

hcodes

H302

pcodes

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Patient-reported goal achievement after antimuscarinic treatment in patients with overactive bladder symptoms.

K-S Lee et al.

International journal of clinical practice, 66(7), 663-670 (2012-06-16)

Standardised traditional outcome measures may fail to address factors that are important to patients and address irrelevant factors. Aim of this study was to assess patient-reported goals and goal achievement (GA) in the antimuscarinic treatment for overactive bladder (OAB) patients.

An evaluation of patient and physician satisfaction with controlled-release oxybutynin 15 mg as a one-step daily dose in elderly and non-elderly patients with overactive bladder: results of the STOP study.

Lorne E Aaron et al.

Current medical research and opinion, 28(8), 1369-1379 (2012-07-10)

Evaluate patient and physician satisfaction with a novel formulation of a once-daily controlled-release (CR) oxybutynin (Uromax*) 15-mg tablet as both the initial and maintenance dose in elderly and non-elderly patients with overactive bladder (OAB). Patients not on anticholinergic treatment for

Clinical effectiveness of early treatment with hyperbaric oxygen therapy for severe late-onset hemorrhagic cystitis after hematopoietic stem cell transplantation in pediatric patients.

Daniele Zama et al.

Pediatric transplantation, 17(1), 86-91 (2012-12-13)

HC is a possible cause of morbidity and extended hospitalization after HSCT. Recent studies have reported the efficiency of HOT in adult patients who underwent allogeneic HSCT, but data in children are scarce. We report our single center experience with

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Global Trade Item Number

SKU	GTIN
O5015-5G	04061833429235
O5015-1G	04061826695128
O5015-500MG	04061833435571