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Merck
CN

P8155

(R)-(−)-Phenylephrine hydrochloride

α-Adrenergic agonist, powder

Synonym(s):

(R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, (R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride

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About This Item

Linear Formula:
HOC6H4CH(CH2NHCH3)OH·HCl
CAS Number:
61-76-7
Molecular Weight:
203.67
NACRES:
NA.77
PubChem Substance ID:
24898912
UNSPSC Code:
12352200
EC Number:
200-517-3
MDL number:
MFCD00012605
Beilstein/REAXYS Number:
4158948
Form:
powder
Quality level:
200

Key Documents

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Product Name

(R)-(−)-Phenylephrine hydrochloride, analytical standard

grade

analytical standard

Quality Level

200

form

powder

packaging

vial of 250 mg

mp

143-145 °C (lit.)

SMILES string

OC1=CC([C@H](CNC)O)=CC=C1.Cl

InChI

1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

InChI key

OCYSGIYOVXAGKQ-FVGYRXGTSA-N

Gene Information

human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)

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Related Categories

Biochem/physiol Actions

α-Adrenergic agonist

Packaging

Supplied in amber screw-cap vials

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H317

Hazard Classifications

Acute Tox. 4 Oral - Skin Sens. 1B

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000355917
0000355917
SLBF1576V
SLBF1576V
106K8803

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C A Boly et al.
British journal of anaesthesia, 111(5), 750-758 (2013-07-11)
Left-ventricular end-systolic elastance (Ees) is an index of cardiac contractility, but the invasive nature of its assessment has limited perioperative application. We explored the feasibility of a minimally invasive method of Ees estimation for perioperative assessment of cardiac function and
Dale A Currigan et al.
Anesthesiology, 121(5), 930-936 (2014-09-10)
Vasopressor drugs, commonly used to treat systemic hypotension and maintain organ perfusion, may also induce regional vasoconstriction in specialized vascular beds such as the lung. An increase in pulmonary vascular tone may adversely affect patients with pulmonary hypertension or right
Doreen Schmidl et al.
Investigative ophthalmology & visual science, 54(3), 1964-1970 (2013-02-27)
We determined whether administration of a nitric oxide synthase (NOS) inhibitor alters optic nerve head blood flow (ONHBF) regulation during isometric exercise in healthy subjects. Our study was done in a randomized, placebo-controlled, double-masked, three-way crossover design. A total of
P F Soeding et al.
British journal of anaesthesia, 111(2), 229-234 (2013-03-23)
The upright sitting or beachchair position is associated with hypotension, risk of cerebral hypoperfusion, and cerebral injury. We hypothesized that by increasing arterial pressure with phenylephrine administration, cerebral perfusion, and postoperative recovery would be improved. Thirty-four patients undergoing elective shoulder
Stephanie W Watts et al.
Arteriosclerosis, thrombosis, and vascular biology, 33(6), 1320-1328 (2013-04-06)
Obesity and hypertension are comorbid in epidemic proportion, yet their biological connection is largely a mystery. The peptide chemerin is a candidate for connecting fat deposits around the blood vessel (perivascular adipose tissue) to arterial contraction. We presently tested the
View All Related Papers

Global Trade Item Number

SKUGTIN
P8155-1VL04061834401070

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