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Merck
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R2751

Ruthenium Red

Powder

Synonym(s):

Ammoniated ruthenium oxychloride

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About This Item

Linear Formula:
[(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
CAS Number:
11103-72-3
Molecular Weight:
786.35
NACRES:
NA.47
PubChem Substance ID:
24278675
UNSPSC Code:
12171500
MDL number:
MFCD00011479
Colour Index Number:
77800

Key Documents

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Product Name

Ruthenium Red, Technical grade

Quality Level

200

assay

34-39% (RUTHENIUM, ICP)

form

powder

technique(s)

microbe id | staining: suitable

solubility

water: 10 mg/mL

εmax

≥150 at 533-534 nm

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

N.N.N.N.N.N.N.N.N.N.N.N.N.N.[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Cl-].[Ru++]O[Ru++]O[Ru++]

InChI

1S/6ClH.14H3N.2O.3Ru/h6*1H;14*1H3;;;;;/q;;;;;;;;;;;;;;;;;;;;;;3*+2/p-6

InChI key

ZXYSDUPLHOJIOR-UHFFFAOYSA-H

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General description

Ruthenium Red is a hexavalent polysaccharide stain. It inhibits mitochondrial Ca2+ uniporter. It is a capsaicin antagonist and blocks vanilloid receptor-1 (VR-1)-coupled ion channels.

Application

Ruthenium Red has been used for microscopic characterization of cotton tip morphology. It has also been used as a TRPV2 channel blocker.
Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels.

signalword

Warning

hcodes

H302

pictograms

Exclamation mark
GHS07

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL4574
BCCM5302
BCCJ8828
BCCH7874
BCCG1965

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Cotton fiber tips have diverse morphologies and show evidence of apical cell wall synthesis
Michael R. Stiff and Candace H. Haigler
Scientific Reports (2016)
George Goodwin et al.
Neuroscience, 429, 10-22 (2019-12-25)
Radiating pain is a significant feature of chronic musculoskeletal pain conditions such as radiculopathies, repetitive motion disorders and whiplash associated disorders. It is reported to be caused by the development of mechanically-sensitive ectopic receptive fields along intact nociceptor axons at
Identification of an Aspartic Residue in the P-loop of the Vanilloid Receptor That Modulates Pore Properties*
Carolina Garcia-MArtinez
The Journal of Biological Chemistry (2000)
Ruthenium red, inhibitor of mitochondrial Ca2+ uniporter, inhibits curcumin-induced apoptosis via the prevention of intracellular Ca2+ depletion and cytochrome c release
Jae Hoon Bae
Biochemical and Biophysical Research Communications, 303 (2003)
TRPC1/TRPC3 channels mediate lysophosphatidylcholine-induced apoptosis in cultured human coronary artery smooth muscles cells
Yuan Wang
Oncotarget, 7(32) (2016)
View All Related Papers

Global Trade Item Number

SKUGTIN
R2751-5G04061836694845
R2751-1G04061836694838

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