S100
Mianserin hydrochloride
analytical standard, for drug analysis
Synonym(s):
1,2,3,4,10,14b-Hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C18H20N2 · HCl
CAS Number:
Molecular Weight:
300.83
UNSPSC Code:
41116107
PubChem Substance ID:
EC Number:
244-426-7
MDL number:
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
solubility
H2O: 3.4 mg/mL, ethanol: 5.6 mg/mL
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
Cl.CN1CCN2C(C1)c3ccccc3Cc4ccccc24
InChI
1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H
InChI key
YNPFMWCWRVTGKJ-UHFFFAOYSA-N
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Antidepressant; antagonist/inverse agonist at 5-HT2 serotonin receptors; also blocks the H1 histamine receptor and the α2 adrenoceptor.
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A C de Luca et al.
Journal of tissue engineering and regenerative medicine, 12(3), 676-686 (2017-05-31)
Adipose-derived stem cells (ASC) are becoming one of the most exploited cells in peripheral nerve repair. They are fast-growing and able to protect neurons from apoptosis; they can reduce post-injury latency and the risk of muscle atrophy. This study evaluates
Yun Gu et al.
Frontiers in pharmacology, 9, 1026-1026 (2018-10-26)
Remyelination is critical for nerve regeneration. However, the molecular mechanism involved in remyelination is poorly understood. To explore the roles of 17β-estradiol (E2) for myelination in the peripheral nervous system, we used a co-culture model of rat dorsal root ganglion
Choongjin Ban et al.
Food chemistry, 302, 125328-125328 (2019-08-14)
To control the oral bioavailability of curcumin, we fabricated solid lipid nanoparticles (SLNs) using tristearin and polyethylene glycol (PEG)ylated emulsifiers. Lipolysis of prepared SLNs via simulated gastrointestinal digestion was modulated by altering the types and concentrations of emulsifiers. After digestion
Global Trade Item Number
| SKU | GTIN |
|---|---|
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| RAB1673-1KT | 04061835172931 |
| RAB1674-1KT | 04061835172948 |
| RAB1676-1KT | 04061835172962 |
| EP5391070018-1EA | 04061835084692 |
| EP5391070034-1EA | 04061835081868 |
| STS0216-250G | 04065266169270 |
| STS0216-1KG | 04065266169263 |
| EP5391070026-1EA | 04061835084708 |
| SAB5600115-100UL | 04061833351307 |
| SAB5600115-1ML | 04022536393995 |
| SAB4200736-100UL | 04061831495515 |
| 449R-16-RUO | 04061837571640 |
| SAB5500172-100UL | 04061837834516 |
| RAB0730-1KT | 04061835165131 |
| SAB5702085-100UL | 04065270653086 |
| SAB4502708-100UG | 04061837745515 |
| ZRB1628-25UL | 04061842574773 |
| ZRB3428-25UL | 04065273082180 |
| ZRB3428-4X25UL | 04065273082197 |
| ZRB1628-4X25UL | 04061842574780 |
| ZRB1672-25UL | 04065269311706 |
| ZRB1672-4X25UL | 04065269312314 |
| ZRB2532-25UL | 04065272116183 |
| ZRB2532-4X25UL | 04065272116190 |