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About This Item
Empirical Formula (Hill Notation):
C17H27NO4
CAS Number:
Molecular Weight:
309.40
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
grade
pharmaceutical primary standard
API family
nadolol
manufacturer/tradename
EDQM
application(s)
pharmaceutical (small molecule)
format
neat
storage temp.
2-8°C
SMILES string
CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12
InChI
1S/C17H27NO4/c1-17(2,3)18-9-12(19)10-22-16-6-4-5-11-7-14(20)15(21)8-13(11)16/h4-6,12,14-15,18-21H,7-10H2,1-3H3/t12?,14-,15+/m1/s1
InChI key
VWPOSFSPZNDTMJ-UCWKZMIHSA-N
Gene Information
human ... ADRB1(153), ADRB2(154)
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Nadolol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Packaging
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.
Other Notes
Sales restrictions may apply.
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Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
监管及禁止进口产品
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R C Heel et al.
Drugs, 20(1), 1-23 (1980-07-01)
Nadolol is a nonselective beta-adrenoceptor blocking drug without intrinsic sympathomimetic or membrane stabilising activity. Its inherently long duration of activity makes it suitable for once daily administration in both hypertension and angina pectoris, and in these conditions it has been
Nadolol: a new beta-adrenoceptor antagonist.
W H Frishman
The New England journal of medicine, 305(12), 678-682 (1981-09-17)
Zsuzsa Jenei-Lanzl et al.
Arthritis & rheumatology (Hoboken, N.J.), 66(9), 2472-2481 (2014-05-14)
Mesenchymal progenitor cell chondrogenesis is the biologic platform for the generation or regeneration of cartilage, but the external influence of the sympathetic nervous system on this process is not yet known. Sympathetic nerve fibers are present in articular tissue, and
Global Trade Item Number
| SKU | GTIN |
|---|---|
| Y0000146 | 04061833794654 |