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Merck
CN

Y0000378

Mitomycin

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Mitomycin C

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About This Item

Empirical Formula (Hill Notation):
C15H18N4O5
CAS Number:
Molecular Weight:
334.33
UNSPSC Code:
41116107
EC Number:
200-008-6
NACRES:
NA.24
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grade

pharmaceutical primary standard

API family

mitomycin

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

N21[C@]([C@H]4N[C@H]4C2)([C@@H](C3=C1C(=O)C(=C(C3=O)N)C)COC(=O)N)OC

InChI

1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1

InChI key

NWIBSHFKIJFRCO-WUDYKRTCSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Mitomycin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.


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pictograms

Skull and crossbonesHealth hazard

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 2 Oral - Carc. 2

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品

This item has



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Yi-fan Feng et al.
Ophthalmic epidemiology, 19(6), 364-370 (2012-11-23)
To assess the efficacy and safety of local application of intraoperative mitomycin C (MMC) at the osteotomy site in primary external dacryocystorhinostomy (EX-DCR). A comprehensive literature search of the Cochrane Library, PubMed and Embase was undertaken to identify relevant trials
Rose K Sia et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(4), 256-264 (2014-04-08)
To compare visual outcomes following photorefractive keratectomy (PRK), PRK with mitomycin C (MMC-PRK), and LASEK in moderate and high myopia in military personnel. This prospective, randomized contralateral eye study included 167 patients 21 years or older with manifest spherical equivalent
Mamoun H Elmamoun et al.
BJU international, 113(5b), E34-E38 (2013-09-24)
To identify a cohort of patients under our care who have had significant and in some cases irreparable damage to their bladders after Mitomycin C (MMC) instillation. To highlight the importance of avoidance and recognition of bladder perforations during transurethral



Global Trade Item Number

SKUGTIN
Y000037804061837568428