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Y0000774

Lansoprazole for peak identification

Name: Lansoprazole for peak identification
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Lansoprazole

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About This Item

Empirical Formula (Hill Notation):

C₁₆H₁₄F₃N₃O₂S

CAS Number:

103577-45-3

Molecular Weight:

369.36

NACRES:

NA.24

PubChem Substance ID:

329831144

UNSPSC Code:

41116107

MDL number:

MFCD00866873

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Properties

grade

pharmaceutical primary standard

API family

lansoprazole

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cc1c(CS(=O)c2nc3ccccc3[nH]2)nccc1OCC(F)(F)F

InChI

1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)

InChI key

MJIHNNLFOKEZEW-UHFFFAOYSA-N

Gene Information

human ... ATP4A(495), ATP4B(496)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lansoprazole for peak identification EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Discovery of lansoprazole and its unique pharmacological properties independent from anti-secretory activity.

Hiroshi Satoh

Current pharmaceutical design, 19(1), 67-75 (2012-09-07)

The proton pump inhibitors (PPIs) lansoprazole (LPZ) and omeprazole (OPZ) have been widely used for more than 20 years in the treatment of acid-related diseases such as gastro-duodenal ulcers and reflux esophagitis. Both LPZ and OPZ are derivatives of 2-[(2-

In vitro and in vivo protection against indomethacin-induced small intestinal injury by proton pump inhibitors, acid pump antagonists, or indomethacin-phosphatidylcholine.

Yun Jeong Lim et al.

Digestion, 86(2), 171-177 (2012-08-22)

Proton pump inhibitors (PPIs) are widely used to prevent nonsteroidal anti-inflammatory drug (NSAID)-induced peptic ulcers. NSAIDs produce small intestinal injury and some PPIs have been reported to protect against NSAID-induced small bowel injury in rats. The aim of this study

Effect of short-term proton pump inhibitor treatment and its discontinuation on chromogranin A in healthy subjects.

Hala H Mosli et al.

The Journal of clinical endocrinology and metabolism, 97(9), E1731-E1735 (2012-06-23)

Chromogranin A (CgA) is used as a generic tumor marker for neuroendocrine tumors. Proton pump inhibitors (PPI) are known to increase CgA, but it is not clear to what extent, and there is little information on how long PPI need

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Global Trade Item Number

SKU	GTIN
Y0000774	04061833804919