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BP041

Betamethasone sodium phosphate

British Pharmacopoeia (BP) Reference Standard

Synonym(s):

Betamethasone 21-phosphate disodium

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About This Item

Empirical Formula (Hill Notation):
C22H28FNa2O8P
CAS Number:
151-73-5
Molecular Weight:
516.40
UNSPSC Code:
41116107
MDL number:
MFCD00200361

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Product Name

Betamethasone sodium phosphate, British Pharmacopoeia (BP) Reference Standard

InChI key

PLCQGRYPOISRTQ-LWCNAHDDSA-L

InChI

1S/C22H30FO8P.2Na/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12,27)18(26)11-31-32(28,29)30;;/h6-7,9,12,15-17,25,27H,4-5,8,10-11H2,1-3H3,(H2,28,29,30);;/q;2*+1/p-2/t12-,15-,16-,17-,19-,20-,21-,22-;;/m0../s1

SMILES string

[Na+].[Na+].[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@H](C)[C@]4(O)C(=O)COP([O-])([O-])=O

grade

pharmaceutical primary standard

API family

betamethasone

form

solid

shelf life

limited shelf life, expiry date on the label

manufacturer/tradename

BP

application(s)

pharmaceutical
pharmaceutical small molecule

format

neat

storage temp.

2-8°C

Gene Information

human ... NR3C1(2908)

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Application

Betamethasone sodium phosphate BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:
  • Dexamethasone Sodium Phosphate Oral Solution
  • Dexamethasone Sodium Phosphate Injection
  • Prednisolone Sodium Phosphate Ear Drops
  • Prednisolone Sodium Phosphate Eye Drops
  • Prednisolone Soluble Tablets
  • Hydrocortisone Sodium Phosphate Oral Solution
  • Betamethasone Eye Drops
  • Hydrocortisone Sodium Phosphate
  • Betamethasone Injection
  • Betamethasone Sodium Phosphate Tablets
  • Hydrocortisone Sodium Phosphate Injection

    • General description

    Betamethasone is a corticosteroid with anti-inflammatory and immunosuppressive abilities, used especially where water retention is undesirable. It is applied as a topical cream, ointment, lotion or gel to treat itching (e.g. from eczema). Corticosteroid used to stimulate fetal lung maturation and to decrease the incidence and mortality from intracranial hemorrhage in premature infants
    This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

    Other Notes

    Sales restrictions may apply.
    Learn how British Pharmacopoeia (BP) sets the standard by offering quality British Pharmacopoeia Chemical Reference Substances (BPCRS).

    Packaging

    Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

    pictograms

    Health hazardExclamation mark
    GHS08,GHS07

    signalword

    Danger

    Hazard Classifications

    Acute Tox. 4 Oral - Repr. 1B - STOT RE 2

    target_organs

    Liver,Kidney,Endocrine system

    Storage Class

    6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

    wgk

    WGK 3

    flash_point_f

    Not applicable

    flash_point_c

    Not applicable

    Regulatory Information

    涉药品监管产品
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