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Merck
CN

L0650000

Lincomycin hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

Lincomycin hydrochloride monohydrate

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About This Item

Empirical Formula (Hill Notation):
C18H34N2O6S · HCl · H2O
CAS Number:
7179-49-9
Molecular Weight:
461.01
NACRES:
NA.24
PubChem Substance ID:
329817369
UNSPSC Code:
41116107
MDL number:
MFCD00167245

Key Documents

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Product Name

Lincomycin hydrochloride, European Pharmacopoeia (EP) Reference Standard

InChI

1S/C18H34N2O6S.ClH.H2O/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4;;/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25);1H;1H2/t9-,10-,11+,12-,13+,14-,15-,16-,18-;;/m1../s1

SMILES string

Cl[H].[H]O[H].CCC[C@@H]1C[C@H](N(C)C1)C(=O)N[C@H]([C@@H](C)O)[C@H]2O[C@H](SC)[C@H](O)[C@@H](O)[C@H]2O

InChI key

LFZGYTBWUHCAKF-DCNJEFSFSA-N

grade

pharmaceutical primary standard

API family

lincomycin

manufacturer/tradename

EDQM

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

pharmaceutical (small molecule)

format

neat

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Related Categories

Application

Lincomycin hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Other Notes

Sales restrictions may apply.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

涉药品监管产品
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P Calza et al.
Environmental science and pollution research international, 20(4), 2262-2270 (2012-08-02)
The aqueous environmental fate of two antibiotics, lincomycin and clarithromycin, and an antiepileptic drug, carbamazepine, was investigated by monitoring drugs decomposition and identifying intermediates in Po river water (North Italy). Initially, control experiments in the dark and under illumination were
Isaac M Hagenbuch et al.
Water research, 46(16), 5028-5036 (2012-07-24)
The role that antibiotics and other "emerging contaminants" play in shaping environmental microbial communities is of growing interest. The use of the prokaryotic metabolic inhibitors tylosin (T), lincomycin (L), and ciprofloxacin (C) in livestock and humans is both global and
PanGyi Kim et al.
Chemosphere, 89(1), 10-18 (2012-05-09)
Chronic toxicity of acetaminophen and lincomycin were evaluated using freshwater organisms including two crustaceans (Daphnia magna and Moina macrocopa) and a fish (Oryzias latipes). H295R, a human adrenal cell was also used to understand the effects on steroidogenesis. In 21
Ulrich Schreiber et al.
Photosynthesis research, 114(3), 165-177 (2013-02-15)
A new type of multi-color PAM chlorophyll fluorometer (Schreiber et al. 2012) was applied for measurements of photodamage to photosystem II (PS II) in optically thin suspensions of Chlorella (200 μg Chl l(-1)) in the presence of 1 mM lincomycin.
Steven L Berry et al.
Veterinary journal (London, England : 1997), 193(3), 654-658 (2012-08-16)
The objective of this study was to observe the dynamics of clinical cure and recurrence of the lesions of bovine digital dermatitis for 11 months after treatment with topical lincomycin HCl. The study was a clinical follow-up of 39 active
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